Drugs / LY518674
last change Mar 2007 re-read 2 minutes ago

LY518674

also known as KB-68984 · LY-674

Small molecule targets PPARA via activation

Developed for
hyperlipidemia · hypertensive disorder · metabolic syndrome X
Investigated by
Eli Lilly and Company · University of Pennsylvania

Trials 4 · a red edge is where a trial was stopped

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00374855 Sep → Nov 2006 hypertensive disorder Eli Lilly and Company Completed No outcome recorded
Phase 2 NCT00327002 Jan → Sep 2006 metabolic syndrome X University of Pennsylvania Completed No outcome recorded
Phase 2 NCT00133380 Jul 2005 → Sep 2006 hyperlipidemia Eli Lilly and Company Completed No outcome recorded
Phase 2 NCT00116519 Jul 2005 → Oct 2006 hyperlipidemia Eli Lilly and Company Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as LY518674 “PPAR Alpha (LY518674): a Phase 2 Dose-Response Study to Evaluate the Blood Pressure-Lowering Effect in Essential Hypertension” NCT00374855
2

“OBJECTIVES: To examine the safety and efficacy of LY518674, a PPAR-alpha agonist.” PMID 17384435 Mar 2007

NCT00327002

Known as KB-68984 ChEMBL registry synonym — accepted as the source's own label CHEMBL424133
Known as LY-674 ChEMBL registry synonym — accepted as the source's own label CHEMBL424133
Action Activate “a PPAR-alpha agonist” PMID 17384435 Mar 2007
Modality Small molecule CHEMBL424133
Target PPARA “a PPAR-alpha agonist” PMID 17384435 Mar 2007