A Study in People With Abnormal Fat Levels in the Blood

Summary

The purposes of this study are to determine: * The safety of the study medication and any side effects that might be associated with it; * Whether the study medication can help patients with low levels of 'good' cholesterol (HDL-C) and high blood fats or triglycerides (TG); * How much of the study medication should be given to patients; * How the study medication compares to fenofibrate (Lofibra), a drug used for people with low levels of HDL-C and high levels of TG.

Timeline

Start

2005-07

Primary completion

—

Completion

2006-10

Publications

• Nissen SE, Nicholls SJ, Wolski K, Howey DC, McErlean E, Wang MD, Gomez EV, Russo JM. Effects of a potent and selective PPAR-alpha agonist in patients with atherogenic dyslipidemia or hypercholesterolemia: two randomized controlled trials. JAMA. 2007 Mar 28;297(12):1362-73. doi: 10.1001/jama.297.12.1362. Epub 2007 Mar 25.

Drugs

Indications