Drugs / ALN-6400
last change Jul 2026 re-read 3 minutes ago

ALN-6400

Developed for
hereditary hemorrhagic telangiectasia · von Willebrand disease (hereditary or acquired)
Investigated by
Alnylam Pharmaceuticals

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT06659640 Nov 2024 → Jan 2028 expected hereditary hemorrhagic telangiectasia Alnylam Pharmaceuticals Active not recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT07575308 Jul 2026 → Jun 2027 expected von Willebrand disease (hereditary or acquired) Alnylam Pharmaceuticals Not yet recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2025-02-25 Alnylam Pharmaceuticals Results Alnylam Highlights Significant Pipeline Progress and Platform Innovation at R&D Day alnylam.com ↗
Data will be shared from the first cohort of participants in the Phase 1 study, demonstrating favorable impact on an ex-vivo hemostasis assay.

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as ALN-6400 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07575308 ↗
1

NCT06659640 ↗

Route Subcutaneous “ALN-6400 will be administered subcutaneously (SC)” NCT06659640 ↗