Drugs / polythiazide
polythiazide
also known as
Nephril · NSC-108161 · P-2525 · Politiazida · Polythiazide component of minizide · Polythiazide component of renese-r · Renese
Small molecule targets SLC12A3 via inhibition
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | RENESE | — | 1961-09-26 | fda.gov ↗ |
Trials 0
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Comparator or background therapy1 trial | ||||||
| — | NCT00684489 Comparator | Sep 2003 → Mar 2005 | essential hypertension | Medical University of South Carolina | Completed | No outcome recorded |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 2 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | polythiazide | “Drugs used were hypertension medications were: chlorothiazide, hydrochlorothiazide, polythiazide indapamide, metolazone” NCT00684489 ↗ |
| Known as | Nephril | ChEMBL registry synonym — accepted as the source's own label CHEMBL1587 ↗ |
| Known as | NSC-108161 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1587 ↗ |
| Known as | P-2525 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1587 ↗ |
| Known as | Politiazida | ChEMBL registry synonym — accepted as the source's own label CHEMBL1587 ↗ |
| Known as | Polythiazide component of minizide | ChEMBL registry synonym — accepted as the source's own label CHEMBL1587 ↗ |
| Known as | Polythiazide component of renese-r | ChEMBL registry synonym — accepted as the source's own label CHEMBL1587 ↗ |
| Known as | Renese | ChEMBL registry synonym — accepted as the source's own label CHEMBL1587 ↗ |
| Action | Inhibit | “Thiazide-sensitive sodium-chloride cotransporter inhibitor” CHEMBL1587 ↗ |
| Modality | Small molecule | — CHEMBL1587 ↗ |
| Target | SLC12A3 | “Thiazide-sensitive sodium-chloride cotransporter inhibitor” CHEMBL1587 ↗ |