Drugs / Admilparant
last change Jun 2026 re-read 2 minutes ago

Admilparant

also known as BMS-986278

Small molecule

Developed for
pulmonary fibrosis · idiopathic pulmonary fibrosis
Investigated by
Bristol-Myers Squibb

Trials 20 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 116 trials
Phase 1 NCT07422298 Feb → Jun 2026 overdue Bristol-Myers Squibb Recruiting No outcome recorded
Phase 1 NCT07225647 Nov 2025 → Jan 2026 Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT06746402 Feb → Sep 2025 Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT06715683 Dec 2024 → Mar 2025 Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT06723535 Dec 2024 → Sep 2025 chronic renal failure syndrome, impaired renal function disease Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT06568458 Sep 2024 → Feb 2025 Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT06425198 Jun → Dec 2024 Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT05985590 Aug → Dec 2023 Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT05932303 Jul → Oct 2023 Bristol-Myers Squibb Completed No outcome recorded
Phase 1 NCT05805904 Mar → May 2023 Bristol-Myers Squibb Completed No outcome recorded
Phase 21 trial
Phase 2 NCT04308681 Jul 2020 → Aug 2022 pulmonary fibrosis Bristol-Myers Squibb Completed No outcome recorded
Phase 33 trials
Phase 3 NCT07441408 Dec 2026 → Nov 2029 expected pulmonary fibrosis Bristol-Myers Squibb Not yet recruiting No outcome recorded
Phase 3 NCT06025578 Oct 2023 → Dec 2027 expected pulmonary fibrosis Bristol-Myers Squibb Active not recruiting No outcome recorded
Phase 3 NCT06003426 Sep 2023 → Oct 2026 expected idiopathic pulmonary fibrosis Bristol-Myers Squibb Active not recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 23 sources stand behind the page.

FieldValueCited text
Known as admilparant Admilparant (BMS-986278) is an oral lysophosphatidic acid receptor 1 antagonist under development for treatment of IPF and PPF.” PMID 40210090 Apr 2025
1

NCT07225647

Known as BMS-986278 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04567667
18

NCT06003426

NCT05985590

NCT06425198

NCT06568458

NCT06715683

NCT03429933

NCT06723535

NCT04468815

NCT03981094

NCT04308681

NCT03712540

NCT06025578

NCT07422298

NCT05684289

NCT05805904

NCT06746402

NCT05932303

NCT07441408

Action Inhibit “is a potent lysophosphatidic acid receptor 1 (LPA1) antagonist” PMID 34709814 Oct 2021
Modality Small molecule CHEMBL5087506
Route Oral Oral administration 30 mg” NCT03712540