drugset / Trial / NCT06723535

A Study to Evaluate BMS-986278 in Participants With Normal Renal Function, Severe Renal Impairment, or End-Stage Renal Disease on Intermittent Hemodialysis

NCT06723535

Phase 1 Completed 27 enrolled Bristol-Myers Squibb
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the effect of severe renal impairment (RI) and end-stage renal disease (ESRD) with intermittent hemodialysis (IHD) on the pharmacokinetics and safety of BMS-986278. This study plans to use a staged design based on RI severity.

Timeline

Start
2024-12-07
Primary completion
2025-09-16
Completion
2025-09-19

Drugs

EvaluationDrugModalityDoseRoute
Subject Admilparant Small molecule