Drugs / Lederfolin
last change Mar 2026 re-read 2 minutes ago

Lederfolin

Developed for
colon carcinoma
Investigated by
Gruppo Oncologico del Nord-Ovest

Trials 1 · a red edge is where a trial was stopped

20222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT05253846 Jan 2022 → Jan 2025 overdue Gruppo Oncologico del Nord-Ovest Active not recruiting No outcome recorded
Also used as a comparator or background therapy in 3 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT07213557 Background Mar 2026 → Sep 2027 expected gastroesophageal cancer National Cancer Institute, Naples Recruiting No outcome recorded
Phase 2 NCT03874026 Background Sep 2019 → May 2023 overdue colorectal cancer National Cancer Institute, Naples Recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT00646607 Comparator Jun 2007 → Apr 2013 colon carcinoma Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente Completed No outcome recorded

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as Lederfolin “mFOLFOX6 (oxaliplatin 85 mg/m2 on day 1 followed by lederfolin 200 mg m2 on day 1, fluorouracil 400 mg m2 on day 1 and 2,400 mg m2 continuous infusion over 46 hours every 2 weeks)” NCT07213557
3

“at half of lederfolin 200 mg/mq 2-hours infusion” NCT03874026

NCT05253846

NCT00646607

Route Intravenous “LEDERFOLIN 200 mg/sqm iv over 2 hours, day 1” NCT05253846