drugset / Trial / NCT05253846

Short-course Radiotherapy Followed by Consolidation Chemotherapy. 2021-001206-29

NCT05253846

Phase 2 Active not recruiting 63 enrolled Gruppo Oncologico del Nord-Ovest
NaSingle-groupOpen-labelTreatment

Summary

The aim of the ShorTrip trail is to evaluate the activity and the safety of total neoadjuvant strategy with FOLFOXIRI as consolidation therapy preceded by short-course radiotherapy and followed by surgery in LARC patients.

Timeline

Start
2022-01-25
Primary completion
2025-01-05
Completion
2028-10-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Irinotecan Small molecule 165 mg/m2 Intravenous
Subject Lederfolin Unknown 200 mg/m2 Intravenous
Subject Oxaliplatin Small molecule 85 mg/m2 Intravenous
Subject fluorouracil Small molecule 3200 mg/m2

Indications

No indication recorded.