Drugs / Oxaliplatin
last change yesterday re-read 8 days ago

Oxaliplatin

Small molecule

Developed for
colorectal cancer · gastric cancer · rectal cancer · malignant pancreatic neoplasm · hepatocellular carcinoma · gastroesophageal junction adenocarcinoma · gastric adenocarcinoma · pancreatic adenocarcinoma
+230 more · pancreatic ductal adenocarcinoma · esophageal cancer · metastasis from malignant tumor of colon · biliary tract cancer · gastroesophageal adenocarcinoma · rectum adenocarcinoma · peritoneal carcinomatosis · rectal carcinoma · colon carcinoma · metastatic malignant neoplasm · esophageal adenocarcinoma · gastric neoplasm · gastroesophageal cancer · intrahepatic cholangiocarcinoma · non-small cell lung carcinoma · diffuse large B-cell lymphoma · colorectal neoplasm · cholangiocarcinoma · colorectal carcinoma · cancer · cancer of unknown primary site · gallbladder cancer · rectal neoplasm · esophageal squamous cell carcinoma · metastatic neoplasm · pancreatic neoplasm · breast cancer · colorectal adenocarcinoma · digestive system cancer · gastric carcinoma · head and neck cancer · liver cancer · ovarian cancer · pancreatic exocrine neoplasm · adenocarcinoma · colon adenocarcinoma · extranodal nasal NK/T cell lymphoma · lung cancer · lymphoma · primary peritoneal carcinoma · carcinoma · malignant colon neoplasm · nasopharyngeal carcinoma · neoplasm of esophagus · ovarian carcinoma · appendix carcinoma · bile duct cancer · digestive system neoplasm · neoplasm · peritoneal carcinoma · rectal signet ring cell adenocarcinoma · rectum mucinous adenocarcinoma · appendix cancer · biliary tract neoplasm · colonic neoplasm · endometrial cancer · germ cell tumor · high grade malignant neoplasm · hilar cholangiocarcinoma · neuroblastoma · non-Hodgkin lymphoma · pancreas disorder · peritoneal neoplasm · small intestine adenocarcinoma · urinary bladder cancer · urothelial carcinoma · B-cell non-Hodgkin lymphoma · Burkitt lymphoma · childhood brain stem glioma · colon mucinous adenocarcinoma · colon signet ring cell adenocarcinoma · extrahepatic bile duct carcinoma · fallopian tube cancer · fallopian tube carcinoma · female breast carcinoma · gallbladder carcinoma · Hodgkins lymphoma · large-cell immunoblastic lymphoma · malignant exocrine pancreas neoplasm · mantle cell lymphoma · mature T-cell and NK-cell non-Hodgkin lymphoma · neuroendocrine neoplasm · osteosarcoma · pancreatic acinar cell carcinoma · periampullary adenocarcinoma · peritoneum cancer · small cell lung carcinoma · small intestine cancer · squamous cell carcinoma · acute myeloid leukemia · aggressive B-cell non-Hodgkin lymphoma · ampulla of vater adenocarcinoma · angioimmunoblastic T-cell lymphoma · appendiceal neoplasm · breast carcinoma · breast neoplasm · carcinoid tumor · carcinoma of esophagus · childhood central nervous system germ cell tumor · childhood ependymoma · chronic lymphocytic leukemia/small lymphocytic lymphoma · colonic disorder · diffuse gastric adenocarcinoma · digestive system neuroendocrine neoplasm · Ewing sarcoma/peripheral primitive neuroectodermal tumor · exocrine pancreatic carcinoma · gallbladder adenocarcinoma · gastric cardia adenocarcinoma · gastric intestinal type adenocarcinoma · grade III lymphomatoid granulomatosis · head and neck squamous cell carcinoma · hepatobiliary neoplasm · hepatoblastoma · hepatoid adenocarcinoma · leukemia · liver and intrahepatic bile duct neoplasm · malignant childhood germ cell neoplasm · melanoma · mesothelioma · myelodysplastic syndrome · ovarian germ cell tumor · ovarian mucinous cystadenocarcinoma · pediatric hepatocellular carcinoma · prostate cancer · refractory malignant neoplasm · relapsed/refractory diffuse large B-cell lymphoma · respiratory system cancer · rhabdomyosarcoma · Richter transformation · stomach carcinoma in situ · teratoma · thyroid cancer · transitional cell carcinoma · triple-negative breast carcinoma · adenocarcinoma of gallbladder and extrahepatic biliary tract · adrenal cortex carcinoma · adult glioblastoma · adult hepatocellular carcinoma · adult T-cell leukemia/lymphoma · ampulla of vater cancer · anal carcinoma · anaplastic large cell lymphoma · anus cancer · B-cell childhood acute lymphoblastic leukemia · bile duct carcinoma · carcinoma of the ampulla of vater · central nervous system germ cell tumor · central nervous system neoplasm · central nervous system teratoma · cerebellar astrocytoma · cervical adenosquamous carcinoma · cervical cancer · childhood central nervous system germinoma · childhood central nervous system mixed germ cell tumor · childhood cerebellar astrocytic neoplasm · childhood cerebral astrocytoma · childhood kidney neoplasm · childhood malignant neoplasm · childhood medulloblastoma · childhood testicular germ cell tumor · classic Hodgkin lymphoma · combined hepatocellular carcinoma and cholangiocarcinoma · cutaneous melanoma · digestive system carcinoma · digestive system disorder · endocrine gland neoplasm · Epstein-Barr virus-associated gastric carcinoma · extragonadal germ cell tumor · extragonadal nonseminomatous germ cell tumor · extragonadal seminoma · fibrolamellar hepatocellular carcinoma · gastric linitis plastica · gastric squamous cell carcinoma · gastrointestinal stromal tumor · giant cell glioblastoma · gliosarcoma · hairy cell leukemia · head and neck neoplasm · hematopoietic and lymphoid cell neoplasm · hepatosplenic T-cell lymphoma · high grade B-cell lymphoma · hormone-resistant prostate carcinoma · intraocular lymphoma · large B-cell lymphoma · large cell carcinoma · low-grade astrocytoma · malignant epithelial tumor of ovary · malignant testicular germ cell tumor · MALT lymphoma · medulloblastoma · metastatic malignant neoplasm in the colon · metastatic malignant neoplasm in the lymph nodes · mucinous adenocarcinoma · mucinous ovarian cancer · mycosis fungoides and variants · neoplastic disease or syndrome · neoplastic syndrome · neuroendocrine carcinoma · nodal marginal zone B-cell lymphoma · nongerminomatous germ cell tumor · optic pathway glioma · pancreatic endocrine carcinoma · pediatric CNS choriocarcinoma · pediatric high-grade glioma · pediatric ovarian germ cell tumor · peripheral T-cell lymphoma, not otherwise specified · peritoneal mesothelioma · post-transplant lymphoproliferative disease · precursor lymphoblastic lymphoma/leukemia · primary cutaneous T-cell non-Hodgkin lymphoma · primary mediastinal large B-cell lymphoma · renal cell carcinoma · renal pelvis/ureter urothelial carcinoma · signet ring cell carcinoma · small intestine lymphoma · supratentorial primitive neuroectodermal tumor · T-cell childhood acute lymphocytic leukemia · T-cell large granular lymphocyte leukemia · testicular cancer · testicular germ cell tumor · tumor of uterus · undifferentiated carcinoma of esophagus · undifferentiated carcinoma of stomach · undifferentiated pancreatic carcinoma · urachus cancer · uterine adnexa cancer · uterine carcinosarcoma · Waldenstrom macroglobulinemia · yolk sac tumor of central nervous system · pleural neoplasm
Investigated by
National Cancer Institute (NCI) · Sanofi · Sun Yat-sen University · Fudan University · Hoffmann-La Roche · M.D. Anderson Cancer Center
+916 more · Genentech, Inc. · Shanghai Zhongshan Hospital · Tianjin Medical University Cancer Institute and Hospital · Alliance for Clinical Trials in Oncology · Bristol-Myers Squibb · Sanofi-Synthelabo · Asan Medical Center · Fujian Cancer Hospital · Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Merck Sharp & Dohme LLC · The First Affiliated Hospital with Nanjing Medical University · GERCOR - Multidisciplinary Oncology Cooperative Group · Peking University Cancer Hospital & Institute · Ruijin Hospital · UNICANCER · Peking University · Zhejiang University · Eli Lilly and Company · Pfizer · Zhejiang Cancer Hospital · Jiangsu HengRui Medicine Co., Ltd. · Memorial Sloan Kettering Cancer Center · Peking Union Medical College Hospital · Massachusetts General Hospital · Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest · Samsung Medical Center · Sixth Affiliated Hospital, Sun Yat-sen University · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · West China Hospital · Yonsei University · Amgen · Chinese PLA General Hospital · Gustave Roussy, Cancer Campus, Grand Paris · Institut du Cancer de Montpellier - Val d'Aurelle · Washington University School of Medicine · Federation Francophone de Cancerologie Digestive · Gruppo Oncologico del Nord-Ovest · Henan Cancer Hospital · ImmunityBio, Inc. · Nanfang Hospital, Southern Medical University · Roche Pharma AG · Roswell Park Cancer Institute · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Case Comprehensive Cancer Center · Chinese Academy of Medical Sciences · City of Hope Medical Center · Dana-Farber Cancer Institute · National Cancer Center, Korea · National Cheng-Kung University Hospital · National Health Research Institutes, Taiwan · RenJi Hospital · Second Affiliated Hospital, School of Medicine, Zhejiang University · University of Miami · Celgene Corporation · European Organisation for Research and Treatment of Cancer - EORTC · First Affiliated Hospital of Zhejiang University · Harbin Medical University · SCRI Development Innovations, LLC · SWOG Cancer Research Network · Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) · The First Affiliated Hospital of Zhengzhou University · Hallym University Medical Center · Liaoning Cancer Hospital & Institute · NSABP Foundation Inc · National Taiwan University Hospital · Qilu Pharmaceutical Co., Ltd. · Seoul National University Hospital · The University of Hong Kong · University Hospital of Crete · University of Chicago · University of Southern California · Xijing Hospital · AstraZeneca · Beth Israel Deaconess Medical Center · all 922 on the full record

Regulatory milestones approvals, filings & regulatory actions · 5 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansions (4) US (FDA) ELOXATIN — 2004-01-09 – 2008-05-21 fda.gov ↗
Approved US (FDA) ELOXATIN — 2002-08-09 fda.gov ↗

Trials 1,746 · started per year

today
US approved 2002
5
19
29
10
18
40
77
66
68
55
56
44
48
57
57
50
45
59
53
56
73
62
79
85
98
98
118
113
101
1998199920002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 010 trials
Phase 0 NCT07254091 Jan 2026 → Jan 2027 expected malignant pancreatic neoplasm Northwell Health Recruiting No outcome recorded
Phase 0 NCT07356466 May 2025 → Apr 2027 expected gastric cancer Fujian Medical University Enrolling by invitation No outcome recorded
Phase 0 NCT05007587 Jul 2021 → Jun 2022 hepatocellular carcinoma Zhejiang Cancer Hospital Unknown No outcome recorded
Phase 0 NCT03970252 Jul 2019 → May 2024 pancreatic ductal adenocarcinoma Jonsson Comprehensive Cancer Center Completed No outcome recorded
Phase 0 NCT03515941 Jun 2018 → Mar 2020 digestive system cancer Tannaz Armaghany Terminated No outcome recorded
Phase 0 NCT03600623 Sep 2017 → Jul 2020 malignant pancreatic neoplasm, pancreatic exocrine neoplasm University of Alabama at Birmingham Terminated No outcome recorded Stop: Enrollment
Phase 0 NCT02896907 Oct 2016 → Mar 2018 pancreatic adenocarcinoma Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University Completed No outcome recorded
Phase 0 NCT02077998 May 2015 female breast carcinoma University of California, Davis Completed No outcome recorded
Phase 0 NCT01992705 Mar 2014 → Sep 2018 pancreatic exocrine neoplasm University of Maryland, Baltimore Completed No outcome recorded
Phase 0 NCT01821612 May 2013 → Nov 2014 pancreatic acinar cell carcinoma, pancreatic ductal adenocarcinoma Alliance for Clinical Trials in Oncology Completed No outcome recorded
Phase 1151 trials
Phase 1 NCT07829185 Dec 2026 → Dec 2029 expected pancreatic ductal adenocarcinoma University of Oklahoma Not yet recruiting No outcome recorded
Phase 1 NCT07859085 Oct 2026 → Mar 2029 expected colorectal neoplasm, pancreatic ductal adenocarcinoma Genentech, Inc. Not yet recruiting No outcome recorded
Phase 1 NCT07060014 Sep 2026 → Sep 2028 expected appendix cancer, small intestine cancer The Methodist Hospital Research Institute Recruiting No outcome recorded
Phase 1 NCT07824934 Sep 2026 → May 2028 expected cancer Sunshine Lake Pharma Co., Ltd. Recruiting No outcome recorded
Phase 1 NCT07649655 Jul 2026 → Mar 2028 expected colorectal cancer Shanghai EpimAb Biotherapeutics Co., Ltd. Not yet recruiting No outcome recorded
Phase 1 NCT07453875 May 2026 → Nov 2027 expected peritoneal carcinomatosis Daping Hospital and the Research Institute of Surgery of the Third Military Medical University Not yet recruiting No outcome recorded
Phase 1 NCT07477743 Mar 2026 → Dec 2027 expected — HC Biopharma Inc. Recruiting No outcome recorded
Phase 1 NCT05296005 Dec 2025 gastric adenocarcinoma, gastroesophageal junction adenocarcinoma Ohio State University Comprehensive Cancer Center Withdrawn No outcome recorded
Phase 1 NCT07030283 Dec 2025 → Jul 2028 expected pancreatic ductal adenocarcinoma University of Colorado, Denver Recruiting No outcome recorded
Phase 1 NCT07059299 Dec 2025 → Aug 2027 expected esophageal adenocarcinoma, gastric adenocarcinoma, gastroesophageal junction adenocarcinoma Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest Recruiting No outcome recorded
Show all 151 trials opens the full record — a long page
Phase 1/2142 trials · 2 met primary · 5 missed
Phase 1/2 NCT07791758 Sep 2026 → Sep 2030 expected colorectal carcinoma Nanjing Leads Biolabs Co.,Ltd Not yet recruiting No outcome recorded
Phase 1/2 NCT07653685 Sep 2026 → Jun 2027 expected colorectal cancer Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT07863869 Sep 2026 → May 2029 expected colorectal cancer Cancer Institute and Hospital, Chinese Academy of Medical Sciences Not yet recruiting No outcome recorded
Phase 1/2 NCT07805551 Aug 2026 → Aug 2030 expected colorectal cancer Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT07522411 Apr 2026 → Dec 2027 expected hepatocellular carcinoma BinYong Liang Not yet recruiting No outcome recorded
Phase 1/2 NCT07453394 Apr 2026 → Apr 2027 expected endometrial cancer, gastric cancer, non-small cell lung carcinoma, ovarian cancer Qilu Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded
Phase 1/2 NCT07595172 Apr 2026 → Aug 2028 expected pancreatic ductal adenocarcinoma West China Hospital Recruiting No outcome recorded
Phase 1/2 NCT07327229 Feb 2026 → Sep 2027 expected gastroesophageal adenocarcinoma Antengene Biologics Limited Recruiting No outcome recorded
Phase 1/2 NCT07282184 Oct 2025 → Jun 2027 expected hepatocellular carcinoma Tongji Hospital Recruiting No outcome recorded
Phase 1/2 NCT07256782 Oct 2025 → Oct 2026 expected neoplastic disease or syndrome Qilu Pharmaceutical Co., Ltd. Recruiting No outcome recorded
Show all 142 trials opens the full record — a long page
Phase 21,088 trials · 19 met primary · 27 missed
Phase 2 NCT07828873 Nov 2026 → Sep 2029 expected gastroesophageal adenocarcinoma The First Affiliated Hospital of Zhengzhou University Not yet recruiting No outcome recorded
Phase 2 NCT07797244 Oct 2026 → Apr 2029 expected colorectal cancer Dai, Guanghai Not yet recruiting No outcome recorded
Phase 2 NCT07711483 Oct 2026 → Oct 2028 expected B-cell non-Hodgkin lymphoma, large B-cell lymphoma Massachusetts General Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07779694 Oct 2026 → Dec 2028 expected rectal carcinoma Zhejiang University Not yet recruiting No outcome recorded
Phase 2 NCT07854600 Oct 2026 → Oct 2028 expected biliary tract cancer Haitao Zhao, MD Recruiting No outcome recorded
Phase 2 NCT07802418 Oct 2026 → Jun 2031 expected malignant pancreatic neoplasm Herlev Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07814417 Oct 2026 → Nov 2028 expected colorectal neoplasm Eli Lilly and Company Not yet recruiting No outcome recorded
Phase 2 NCT07802288 Sep 2026 → Apr 2029 expected gastroesophageal adenocarcinoma Tianjin Medical University Cancer Institute and Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07847710 Sep 2026 → Mar 2028 expected intrahepatic cholangiocarcinoma The First Affiliated Hospital with Nanjing Medical University Recruiting No outcome recorded
Phase 2 NCT07815288 Sep 2026 → Dec 2029 expected colorectal adenocarcinoma Peking University Cancer Hospital & Institute Not yet recruiting No outcome recorded
Show all 1,088 trials opens the full record — a long page
Phase 2/349 trials · 6 met primary · 8 missed
Phase 2/3 NCT07866313 Jun 2026 → Aug 2028 expected colorectal cancer Changhai Hospital Recruiting No outcome recorded
Phase 2/3 NCT07490262 Mar 2026 → Dec 2027 expected hepatocellular carcinoma Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. Recruiting No outcome recorded
Phase 2/3 NCT06904170 Nov 2025 → Sep 2029 expected hepatocellular carcinoma UNICANCER Recruiting No outcome recorded
Phase 2/3 NCT06841679 Aug 2025 → Sep 2030 expected gastroesophageal adenocarcinoma Beijing Biostar Pharmaceuticals Co., Ltd. Recruiting No outcome recorded
Phase 2/3 NCT06028737 Mar 2025 → Apr 2027 expected gastric adenocarcinoma, gastroesophageal cancer, gastroesophageal junction adenocarcinoma Ukrainian Society of Clinical Oncology Recruiting No outcome recorded
Phase 2/3 NCT06758830 Jan 2025 → Dec 2029 expected rectal cancer National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos Recruiting No outcome recorded
Phase 2/3 NCT06441565 May 2024 → Dec 2025 overdue colorectal cancer Sun Yat-sen University Recruiting No outcome recorded
Phase 2/3 NCT06279130 Jan 2024 → Jan 2029 expected — The Netherlands Cancer Institute Recruiting No outcome recorded
Phase 2/3 NCT05976568 Sep 2023 → Sep 2027 expected hepatocellular carcinoma Qilu Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded
Phase 2/3 NCT05980481 Aug 2023 → Jul 2025 overdue gastric cancer RemeGen Co., Ltd. Active not recruiting No outcome recorded
Phase 3209 trials · 27 met primary · 31 missed
Phase 3 NCT07584135 May 2026 → Jan 2029 expected gastric adenocarcinoma NingBo Junyan Hongshi Biosciences Co., Ltd Recruiting No outcome recorded
Phase 3 NCT06783491 May 2026 → Jun 2030 expected colorectal carcinoma Maimónides Biomedical Research Institute of Córdoba Recruiting No outcome recorded
Phase 3 NCT07277842 Dec 2025 → Dec 2028 expected rectum adenocarcinoma Sun Yat-sen University Not yet recruiting No outcome recorded
Phase 3 NCT07366528 Dec 2025 → Oct 2028 expected gastric cancer Ruijin Hospital Recruiting No outcome recorded
Phase 3 NCT07118800 Dec 2025 → Dec 2030 expected rectum adenocarcinoma UNICANCER Not yet recruiting No outcome recorded
Phase 3 NCT06346197 Dec 2025 → May 2028 expected gastric cancer, metastatic malignant neoplasm Centre Leon Berard Recruiting No outcome recorded
Phase 3 NCT07238283 Dec 2025 → Oct 2028 expected — Jiangsu HengRui Medicine Co., Ltd. Recruiting No outcome recorded
Phase 3 NCT07235930 Nov 2025 → Jul 2029 expected exocrine pancreatic carcinoma Zhejiang Cancer Hospital Recruiting No outcome recorded
Phase 3 NCT07267806 Oct 2025 → Oct 2029 expected chemotherapy-induced toxicity, hepatocellular carcinoma Linhui Peng Recruiting No outcome recorded
Phase 3 NCT07188025 Oct 2025 → Oct 2030 expected rectal cancer Erasmus Medical Center Recruiting No outcome recorded
Show all 209 trials opens the full record — a long page
Phase 425 trials · 1 met primary
Phase 4 NCT07801027 Nov 2026 → Jan 2030 expected biliary tract cancer, gastric neoplasm, gastroesophageal junction adenocarcinoma, uterine cervix neoplasm Merck Sharp & Dohme LLC Not yet recruiting No outcome recorded
Phase 4 NCT07790445 Jul 2026 → Dec 2028 expected biliary tract cancer Zhai Wenlong Recruiting No outcome recorded
Phase 4 NCT07446465 Mar 2026 → Jan 2027 expected colorectal cancer Ye Xu Not yet recruiting No outcome recorded
Phase 4 NCT06931808 Mar 2025 → Mar 2026 overdue rectum adenocarcinoma First Affiliated Hospital of Ningbo University Enrolling by invitation No outcome recorded
Phase 4 NCT06550453 Sep 2024 → Jan 2025 overdue colorectal carcinoma yangjianjun Recruiting No outcome recorded
Phase 4 NCT06417606 May 2024 → Apr 2025 intrahepatic cholangiocarcinoma Zhiyong Huang Unknown No outcome recorded
Phase 4 NCT06311916 May 2024 → Dec 2027 expected hepatocellular carcinoma Chen Xiaoping Not yet recruiting No outcome recorded
Phase 4 NCT06311942 Apr 2024 → Dec 2027 expected hepatocellular carcinoma Chen Xiaoping Recruiting No outcome recorded
Phase 4 NCT05634720 Jan 2024 → Nov 2025 overdue pancreatic ductal adenocarcinoma Duke University Active not recruiting No outcome recorded
Phase 4 NCT05203172 Jul 2022 → Jul 2029 expected cancer Pfizer Recruiting No outcome recorded
Phase not applicable69 trials · 1 met primary · 2 missed
— NCT07854964 Oct 2026 → May 2030 expected — Tang-Du Hospital Not yet recruiting No outcome recorded
— NCT07859410 Oct 2026 → Oct 2028 expected gastroesophageal junction adenocarcinoma Anhui Medical University Not yet recruiting No outcome recorded
— NCT07613905 Sep 2026 → Dec 2028 expected hypersensitivity reaction disease Fujian Cancer Hospital Not yet recruiting No outcome recorded
— NCT07542912 Jun 2026 → Jun 2029 expected — Sun Yat-sen University Not yet recruiting No outcome recorded
— NCT07855757 Jun 2026 → Jun 2028 expected gastric cancer, peritoneal carcinomatosis Zhejiang Cancer Hospital Active not recruiting No outcome recorded
— NCT07618546 May 2026 → Mar 2027 expected hepatocellular carcinoma Henan Cancer Hospital Not yet recruiting No outcome recorded
— NCT07283939 Feb 2026 → May 2030 expected appendix carcinoma, cancer of unknown primary site, carcinoma of esophagus, carcinoma of the ampulla of vater +3 Alliance for Clinical Trials in Oncology Recruiting No outcome recorded
— NCT07474103 Nov 2025 → Mar 2028 expected rectum adenocarcinoma Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Recruiting No outcome recorded
— NCT07334587 Sep 2025 → Feb 2026 overdue colorectal carcinoma Allama Iqbal Medical College Enrolling by invitation No outcome recorded
— NCT06893887 May 2025 → Dec 2027 expected hepatocellular carcinoma Nanjing Tianyinshan Hospital Recruiting No outcome recorded
Phase not stated3 trials · 1 met primary
— NCT02436044 — hepatic vascular disorder, hepatocellular carcinoma Ming Zhao Approved for marketing No outcome recorded
— NCT01216124 — triple-negative breast carcinoma Fudan University Available No outcome recorded
— NCT00786058 — malignant pancreatic neoplasm CONKO-Studiengruppe Approved for marketing Met primary
Comparator or background therapy1,126 trials
Phase 0 NCT07328087 Background Feb 2026 → Dec 2030 expected colorectal cancer Biogenea Pharmaceuticals Ltd. Recruiting No outcome recorded
Phase 0 NCT07167446 Background Oct 2025 → Sep 2027 expected chemotherapy-induced neuropathy, colorectal cancer Fox Chase Cancer Center Recruiting No outcome recorded
Phase 0 NCT07034742 Background Jun 2025 → Jan 2026 overdue gastric adenocarcinoma Cancer Institute and Hospital, Chinese Academy of Medical Sciences Recruiting No outcome recorded
Phase 0 NCT06525714 Background Aug 2024 → Jul 2029 expected gastric cancer The First Hospital of Jilin University Not yet recruiting No outcome recorded
Phase 0 NCT06011772 Background Dec 2023 → Feb 2026 overdue colorectal cancer Roswell Park Cancer Institute Active not recruiting No outcome recorded
Show all 1,126 trials opens the full record — a long page

Press releases naming this drug 16 releases

DateIssuerRelease
2026-10-09 Hoffmann-La Roche FDA approves Roche’s Tecentriq in combination with a fluoropyrimidine and oxaliplatin for the adjuvant treatment of a certain type of stage III colon cancer roche.com ↗
2026-10-08 Genentech, Inc. FDA Approves Genentech’s Tecentriq in Combination With a Fluoropyrimidine and Oxaliplatin for The Adjuvant Treatment of a Certain Type of Stage III Colon Cancer gene.com ↗
2025-11-17 PharmaEngine ONIVYDE® with oxaliplatin, fluorouracil and leucovorin will be included in Taiwan NHI for first-line treatment of metastatic pancreatic adenocarcinoma pharmaengine.com ↗
2021-11-25 Ono Pharmaceutical Co., Ltd. ONO Receives Approval of Opdivo® (nivolumab) for Expanded Use for Two Indications in Japan - First-line Treatment of Unresectable Advanced or Recurrent Gastric Cancer in Combination with Chemotherapy - Adjuvant Treatment of Esophageal Cancer PDF(192 KB) @media screen and (max-width: 767px){ .mod__table-data { min-width: 100px !important; } } Ono Pharmaceutical Co., Ltd. (Osaka, Japan; President, Representative Director, Gyo Sagara; “ONO”) and Bristol-Myers Squibb K.K. (Shinjuku, Tokyo; President, Jean-Christophe Barland) today announced that ONO has received the approvals of Opdivo® (generic name: nivolumab) Intravenous Infusion (“Opdivo”), a human anti-PD-1 monoclonal antibody in Japan, for expanded use for the first-line treatment of unresectable advanced or recurrent gastric cancer in combination with chemotherapy, and adjuvant treatment of esophageal cancer, for a partial change in approved items of the manufacturing and marketing approval. 〈Approval for the first-line treatment of unresectable advanced or recurrent gastric cancer〉 This approval is based on the results from the following 2 clinical studies: CheckMate -649 study (ONO-4538-44): A global multi-center, randomized, open-label Phase 3 clinical study, evaluating Opdivo plus chemotherapy or Opdivo plus Yervoy (ipilimumab) combination compared to chemotherapy alone in patients with previously untreated, non-human epidermal growth factor receptor 2 (non-HER2)-positive, unresectable advanced or recurrent gastric cancer (GC), gastroesophageal junction cancer (GEJC) or esophageal adenocarcinoma (ESA), conducted on a world-wide basis including Japan, South Korea and Taiwan In this study, Opdivo plus chemotherapy showed a statistically significant and clinically meaningful improvement in overall survival (OS) both in all randomized patient population and OS in PD-L1 positive patients with a combined positive score (CPS) ≥5, one of the primary endpoints, versus chemotherapy. Furthermore, Opdivo plus chemotherapy demonstrated a statistically significant extension in progression-free survival (PFS) in PD-L1 positive patients with CPS ≥5, the other primary endpoint, versus chemotherapy. The safety profile of Opdivo plus chemotherapy in the study was consistent with the known safety profiles of the individual treatments. ATTRACTION-4 study (ONO-4538-37): A multi-center, randomized Phase 2/3 clinical study, evaluating Opdivo plus chemotherapy compared to placebo plus chemotherapy in patients with previously untreated, HER-2 negative, unresectable advanced or recurrent GC or GEJC, conducted in Japan, South Korea and Taiwan In this study, Opdivo plus chemotherapy showed a statistically significant extension in PFS, one of the primary endpoints, versus placebo plus chemotherapy. On the other hand, Opdivo plus chemotherapy did not demonstrate a statistically significance in OS, the other of the primary endpoints. The safety profile of Opdivo plus chemotherapy in the study was consistent with the known safety profiles of the individual treatments. About CheckMate -649 study (ONO-4538-44) Checkmate -649 is a multi-center, randomized, open-label Phase 3 clinical study, evaluating Opdivo plus chemotherapy or Opdivo plus Yervoy combination compared to chemotherapy alone in patients with previously untreated, non-HER2-positive, unresectable advanced or recurrent gastric cancer, gastroesophageal junction cancer or esophageal adenocarcinoma. Patients in the Opdivo plus chemotherapy arm received Opdivo 240 mg plus fluorouracil, calcium folinate and oxaliplatin (FOLFOX) every two weeks or Opdivo 360 mg plus capecitabine and oxaliplatin (CapeOX) every three weeks. Patients in the chemotherapy arm received FOLFOX or CapeOX every two or three weeks, respectively. All patients continued treatment up to two years or until disease progression, unacceptable toxicity or withdrawal of consent. The primary endpoints of the study are overall survival (OS) in PD-L1 positive patients with a combined positive score (CPS) ≥ 5 treated with Opdivo plus chemotherapy and progression-free survival (PFS) in CPS ≥ 5 patients treated with Opdivo plus chemotherapy. Key secondary endpoint is OS in CPS ≥ 1 and all-randomized patients treated with Opdivo plus chemotherapy. About ATTRACTION-4 study (ONO-4538-37) ATTRACTION-4 study is a multi-center, randomized Phase 2/3 clinical study, evaluating Opdivo plus chemotherapy (oxaliplatin + S-1 or capecitabine) compared to placebo plus chemotherapy in patients with previously untreated, HER2 negative unresectable advanced or recurrent gastric cancer or gastroesophageal junction cancer. Patients received Opdivo 360 mg or placebo every 3 weeks until disease progression or unacceptable toxicity is observed. The primary endpoints of the study are progression-free survival (PFS) and overall survival (OS). About Gastric cancer It is estimated that about 138,000 new cases 1) are diagnosed with gastric cancer per year in Japan (about 1,089,000 cases worldwide 2) ) and approximately 46,000 deaths 1) (about 768,000 worldwide 2) ) per year resulting from this disease 1) , which is the 2nd most common type of cancer after lung cancer in Japan. As there has been little progression in the standard of care of first-line chemotherapy for the HER2 negative unresectable, advanced or recurrent gastric cancer in the past decade in Japan, an innovative treatment option is needed in this patient population. Globocan 2020: Stomach Cancer, Japan, World Health Organization https://gco.iarc.fr/today/data/factsheets/populations/392-japan-fact-sheets.pdf Globocan 2020: Stomach Cancer, World, World Health Organization https://gco.iarc.fr/today/data/factsheets/populations/900-world-fact-sheets.pdf 〈Approval for the adjuvant treatment of esophageal cancer〉 This approval is based on the results from a global multi-center, randomized, double-blind Phase 3 clinical study, CheckMate -577 study (ONO-4538-43), evaluating Opdivo monotherapy as an adjuvant treatment in patients with resected esophageal cancer (ESC) or gastroesophageal junction cancer (GEJC) compared to placebo. In this study, Opdivo showed a statistically significant improvement in disease-free survival (DFS), the primary endpoint of the study, compared to placebo. The safety profile of Opdivo in this study was consistent with previously reported studies of Opdivo monotherapy. About CheckMate -577 study (ONO-4538-43) CheckMate -577 study is a global multi-center, randomized, double-blind Phase 3 clinical study, evaluating Opdivo monotherapy as an adjuvant treatment in patients with resected esophageal cancer or gastroesophageal junction cancer (GEJC) who have received chemoradiation therapy (CRT) and have not achieved a pathological complete response. Following neoadjuvant CRT and complete tumor surgical resection (also known as trimodality therapy), patients were randomized to receive Opdivo or placebo. In patients receiving Opdivo, it was administered at 240 mg every two weeks for 16 weeks followed by Opdivo 480 mg every four weeks until disease recurrence, unacceptable toxicity or withdrawal of consent, with a maximum of one year total treatment duration. The primary endpoint of the study is disease-free survival (DFS) and the secondary endpoint is overall survival (OS). About esophageal cancer Esophageal cancer is a malignant tumor that occurs in the inner layer (mucosa) of the esophagus and grows outside (toward the deeper layer). There are two main histological types of esophageal cancer; squamous cell carcinoma (SCC) and adenocarcinoma. SCC is the predominant type accounting for about 90% of all esophageal cancer in Japan. It is estimated that about 26,000 new cases1) are diagnosed with esophageal cancer per year in Japan (about 604,000 cases worldwide 2) ) and approximately 12,000 deaths 1) (about 544,000 worldwide 2) ) per year resulting from this disease. In Japan, radical resection following neoadjuvant therapy is performed as a treatment for resectable locally advanced esophageal cancer that does not have distant metastasis, but recurrence has been observed in 28-47% after radical resection. Furthermore, since the prognosis of recurrent cases after radical resection of esophageal cancer is extremely poor 3) , it is considered that there is a high medical need for postoperative adjuvant therapy aimed at suppressing recurrence. Globocan 2020: Esophageal Cancer, Japan, World Health Organization Available at: https://gco.iarc.fr/today/data/factsheets/populations/392-japan-fact-sheets.pdf Globocan 2020: Esophageal Cancer, World, World Health Organization Available at: https://gco.iarc.fr/today/data/factsheets/populations/900-world-fact-sheets.pdf Guideline for Diagnosis and Treatment of Carcinoma of the Esophagus 2017, The Japan Esophageal Society Overview of Opdivo® Intravenous Infusion Product name Opdivo® Intravenous Infusion 20mg, 100mg, 120mg and 240mg Generic name (JAN) Nivolumab (Genetical recombination) Indication Melanoma Unresectable, advanced or recurrent non-small cell lung cancer Unresectable or metastatic renal cell carcinoma Recurrent or refractory classical Hodgkin lymphoma Recurrent or metastatic head and neck cancer Unresectable advanced or recurrent gastric cancer that has progressed after chemotherapy Unresectable advanced or recurrent malignant pleural mesothelioma Microsatellite instability high (MSI-High) unresectable advanced or recurrent colorectal cancer that has progressed after chemotherapy Unresectable advanced or recurrent esophageal cancer that has progressed after chemotherapy Adjuvant treatment of esophageal cancer Dosage and administration 〈Melanoma〉 Usually, for adults, administer at 240 mg of nivolumab every 2 weeks or 480 mg every 4 weeks as intravenous infusion. In the adjuvant treatment of melanoma, the administration period does not exceed 12 months. In combination therapy with ipilimumab for unresectable melanoma, usually, for adults, administer 80 mg of nivolumab every 3 weeks for 4 doses. After that, administer 240 mg of nivolumab every 2 weeks or 480 mg every 4 weeks as intravenous infusion. 〈Unresectable, advanced or recurrent non-small cell lung cancer , and unresectable advanced or recurrent gastric cancer that has progressed after chemotherapy 〉 Usually, for adults, administer at 240 mg of nivolumab every 2 weeks or 480 mg every 4 weeks as intravenous infusion. In combination therapy with other anti-tumor drugs, usually, for adults, administer 240 mg of nivolumab every 2 weeks or 360 mg every 3 weeks as intravenous infusion. 〈Unresectable or metastatic renal cell carcinoma〉 Usually, for adults, administer 240 mg of nivolumab every 2 weeks or 480 mg every 4 weeks as intravenous infusion. In combination with cabozantinib, usually, for adults, administer 240 mg of nivolumab every 2 weeks or 480 mg every 4 weeks as intravenous infusion. In combination therapy with ipilimumab for unresectable or metastatic renal cell carcinoma previously untreated with chemotherapy, usually, for adults, administer 240 mg of nivolumab as intravenous infusion every 3 weeks for 4 doses. After that, administer 240 mg of nivolumab every 2 weeks or 480 mg every 4 weeks as intravenous infusion. 〈Recurrent or refractory classical Hodgkin lymphoma〉 Usually, for adults, administer 240 mg of nivolumab every 2 weeks or 480 mg every 4 weeks as intravenous infusion. Usually for pediatrics, administer 3 mg/kg (body weight) of nivolumab every 2 weeks as intravenous infusion. For pediatrics weighing 40 kg (body weight) or more, nivolumab can be administered at 240 mg of every 2 weeks or 480 mg every 4 weeks as intravenous infusion. 〈Recurrent or metastatic head and neck cancer〉 Usually, for adults, administer 240 mg of nivolumab every 2 weeks or 480 mg every 4 weeks as intravenous infusion. 〈Unresectable advanced or recurrent malignant pleural mesothelioma〉 Usually, for adults, administer 240 mg of nivolumab every 2 weeks or 480 mg every 4 weeks as intravenous infusion. In combination therapy with ipilimumab, usually, for adults, administer 240 mg of nivolumab every 2 weeks or 360 mg every 3 weeks as intravenous infusion. 〈Microsatellite instability high (MSI-High) unresectable advanced or recurrent colorectal cancer that has progressed after chemotherapy〉 Usually, for adults, administer at 240 mg of nivolumab every 2 weeks or 480 mg every 4 weeks as intravenous infusion. In combination therapy with ipilimumab, usually, for adults, administer 240 mg of nivolumab as intravenous infusion every 3 weeks for 4 doses. After that, administer 240 mg of nivolumab every 2 weeks or 480 mg every 4 weeks as intravenous infusion. 〈Unresectable advanced or recurrent esophageal cancer that has progressed after chemotherapy, and adjuvant treatment of esophageal cancer〉 Usually, for adults, administer 240 mg of nivolumab every 2 weeks or 480 mg every 4 weeks as intravenous infusion. In the adjuvant treatment of esophageal cancer, the administration period does not exceed 12 months. 〈 Recurrent or metastatic head and neck cancer, unresectable advanced or recurrent gastric cancer that has progressed after chemotherapy, and unresectable advanced or recurrent esophageal cancer that has progressed after chemotherapy〉 Usually, for adults, administer 240 mg of nivolumab every 2 weeks or 480 mg every 4 weeks as intravenous infusion. Manufacturer/distributor Ono Pharmaceutical Co., Ltd. Co-promotion Bristol-Myers Squibb K.K. Note: Underlined parts show the revised ones according to this approval. About Opdivo Opdivo is a programmed death-1 (PD-1) immune checkpoint inhibitor that is designed to uniquely harness the body’s own immune system to help restore anti-tumor immune response by blocking the interaction between PD-1 and its ligands. By harnessing the body’s own immune system to fight cancer, Opdivo has become an important treatment option across multiple cancers since the approval for the treatment of melanoma in Japan in July 2014. Opdivo is currently approved in more than 65 countries, including Japan, South Korea, Taiwan, China, the US and European Union. In Japan, ONO launched Opdivo for the treatment of unresectable melanoma in September 2014. Thereafter, Opdivo received an approval for additional indications of unresectable, advanced or recurrent non-small cell lung cancer in December 2015, unresectable or metastatic renal cell carcinoma in August 2016, relapsed or refractory classical Hodgkin lymphoma in December 2016, recurrent or metastatic head and neck cancer in March 2017, unresectable advanced or recurrent gastric cancer which has progressed after chemotherapy in September 2017, unresectable advanced or recurrent malignant pleural mesothelioma which has progressed after chemotherapy in August 2018, and microsatellite instability high (MSI-High) unresectable advanced or recurrent colorectal cancer that has progressed following chemotherapy and unresectable advanced or recurrent esophageal cancer that has progressed following chemotherapy in February 2020. In addition, ONO has submitted supplemental applications for the adjuvant treatment of urothelial cancer and cancer of unknown primary, and is conducting clinical development program including hepatocellular carcinoma, ovarian cancer, bladder cancer, prostate cancer, pancreatic cancer, biliary tract cancer, etc. About the ONO and Bristol-Myers Squibb Collaboration In 2011, through a collaboration agreement with Bristol-Myers Squibb (BMS), ONO granted BMS its territorial rights to develop and commercialize Opdivo globally except in Japan, South Korea and Taiwan, where ONO had retained all rights to Opdivo except the US at the time. In July 2014, ONO and BMS further expanded the companies’ strategic collaboration agreement to jointly develop and commercialize multiple immunotherapies – as single agent and combination regimens – for patients with cancer in Japan, South Korea and Taiwan. Back to List ono-pharma.com ↗
2018-07-11 Bristol-Myers Squibb Bristol-Myers Squibb’s Opdivo® (nivolumab) + Low-Dose Yervoy® (ipilimumab) is the First Immuno-Oncology Combination Approved for MSI-H/dMMR mCRC Patients Who Progressed Following Treatment with a Fluoropyrimidine, Oxaliplatin and... bms.com ↗
2017-08-01 Bristol-Myers Squibb Bristol-Myers Squibb Receives FDA Approval for Opdivo (nivolumab) in MSI-H or dMMR Metastatic Colorectal Cancer That Has Progressed Following Treatment with a Fluoropyrimidine, Oxaliplatin, and Irinotecan bms.com ↗
2010-06-26 Sun Pharmaceutical Industries, Inc. Sun Pharma: an update on generic Eloxatin® injection sunpharma.com ↗
2010-04-01 Teva Branded Pharmaceutical Products R&D, Inc. Teva Settles Generic Eloxatin Litigation tevapharm.com ↗
2009-08-11 Sun Pharmaceutical Industries, Inc. Generic Eloxatin® and Imitrex® approval: shares 180-day marketing drug exclusivity for generic Eloxatin® sunpharma.com ↗
2009-08-11 Teva Branded Pharmaceutical Products R&D, Inc. Teva Announces Approval And Launch of Oxaliplatin Injection tevapharm.com ↗
2005-03-21 Debiopharm International SA Debiopharm announces import approval from Elplat® (Oxaliplatin) in Japan debiopharm.com ↗
2005-02-07 Debiopharm International SA Debiopharm S.A. announces marketing approval for a new formulation of Eloxatin® (Oxaliplatin for injection) debiopharm.com ↗

Evidence & citations 34 cited values

Every value below carries the sentence it was read from. 2,881 sources stand behind the page.

FieldValueCited text
Known as oxaliplatin “Adjuvant chemotherapy: FOLFOX6 regiment : Oxaliplatin(Hengrui Medicine Co., Ltd,China) 85mg/m2 IV d1, Leucovorin (Hengrui Medicine Co., Ltd,China)400mg/m2 IV d1, 5-FU(Hengrui...” NCT01889303 ↗
2858

“Cetuximab 500mg/m² + envafolimab 200mg + irinotecan 150 mg/m² + oxaliplatin 85 mg/m² + leucovorin 200 mg/m² + 5-FU 2400 mg/m² civ. 46h all on day 1 of each 2 weeks cycle up to...” NCT05959356 ↗

“Oxaliplatin will be administered intravenously at a dose of 100 mg/m\^2 along with folinic acid administration intravenously at a dose of 400 mg/m\^2 (racemic) or 200 mg/m\^2...” NCT00778830 ↗

“After 24 weeks of induction therapy with either fluorouracil plus leucovorin plus oxaliplatin or capecitabine plus oxaliplatin, both with bevacizumab, patients without disease...” PMID 26361971 ↗ Sep 2015

“The dosing regimen during the dose escalation phase will include three different doses of fruquintinib (3 mg, 4 mg and 5 mg, per oral, once per day days 1-14) + sintilimab,...” PMID 41005780 ↗ Sep 2025

“After achieving objective tumor response or stable disease after 3 cycles of capecitabine and oxaliplatin or 4 cycles of 5-fluorouracil and oxaliplatin with or without...” PMID 41837962 ↗ Apr 2026

“Oxaliplatin 85 mg/m2 intravenously on day 1; Leucovorin 200 mg/m2 IV(in vein) from hour 0 to 2 on days 1 and 2; and Fluorouracil 400 mg/m2 IV bolus at hour 2, then 600mg/m2...” NCT02527772 ↗

“The neoadjuvant treatment regimen will consist of Oxaliplatin at a dose of 130mg/m2, administered intravenously over a period of more than 2 hours on Day 1, every 3 weeks; and...” NCT06014372 ↗

“Hepatic Arterial Infusion Chemotherapy: FOLFOX6 regimen was infused with chemotherapy drugs: oxaliplatin 130 mg/m2 infusion for 2 hours, folinate calcium 400 mg/m2 infusion for...” NCT05290116 ↗

“patients with locally advanced or metastatic BTC and an Eastern Cooperative Oncology Group performance status of 0 or 1 were randomly assigned (1:1) to receive oxaliplatin,...” PMID 34662180 ↗ Oct 2021

“Oxaliplatin 85 mg/m2 IV, folinic acid 400 mg/m2 IV (or L-folinic acid 200 mg/m²), and fluorouracil (5-FU) 400 mg/m² IV bolus; followed by 5 FU 2400 mg/m2 as a 46 hour...” NCT06846346 ↗

Show 2,848 more sources

Known as 205803BIJ “OXALIPLATIN (205803BIJ)” NCT02191566 ↗
Known as diaminocyclohexane-platinum “Oxaliplatin, diaminocyclohexane-platinum, is an alkylating agent inhibiting DNA replication” NCT00786006 ↗
Known as Eloxatin “Oxaliplatin(Eloxatin®) + 5-FU/LV (FOLFOX4) Compared With Single Agent Doxorubicin (Adriamycin®) as Palliative Chemotherapy in Advanced Hepatocellular Carcinoma Patients...” NCT00471965 ↗
33

“A Phase II Study of Oxaliplatin (Eloxatin) Capecitabine (Xeloda) and Pre-operative Radiotherapy for Patients With Locally Advanced and Inoperable Rectal Cancer.” NCT00220051 ↗

“Phase I Study of Oxaliplatin (Eloxatin) and Capecitabine (Xeloda) and Concurrent Radiation Therapy (XELOX-RT) in Non-Small Cell Lung Cancer” NCT00268151 ↗

“a two-hours intravenous infusion of Oxaliplatin (Eloxatin ®) at 130 mg/m 2, 20 min after raltitrexed, on days 1, 17, 35.” NCT02723253 ↗

“based on 5-fluorouracil, folinic acid, and oxaliplatin (Eloxatin®), with the EGF receptor antibody cetuximab (Erbitux®)” NCT00145314 ↗

“OX - oxaliplatin (Eloxatin), a platinum-based antineoplastic agent, which inhibits DNA repair and/or DNA synthesis” NCT05262452 ↗

“oral Xeloda with intravenous (IV) Eloxatin (oxaliplatin) and IV bevacizumab (Avastin) as a first-line treatment” NCT00118755 ↗

“the combination of the chemotherapeutic agents capecitabine (Xeloda) and oxaliplatin (Eloxatin)” NCT00394992 ↗

“Oxaliplatin (Eloxatin) at 65 mg/m2 given as a 2-hr IV infusion via a central venous port” NCT03374852 ↗

“Eloxatin (oxaliplatin), leucovorin (folinic acid) and 5-Fluorouracil (5-FU)” NCT00265850 ↗

“Oxaliplatin (Eloxatin), 5FU (5-Fluorouracil) and Leucovorin (Folinic Acid)” NCT00580073 ↗

Show 23 more sources

Known as Eloxatin (oxaliplatin) “Eloxatin (oxaliplatin)” NCT00517829 ↗
Known as Eloxatinâ “Phase II Study of the A-ICOX Regimen Consisting of Bevacizumab (Avastinâ), Intermittent Dose Capecitabine (Xelodaâ) and Oxaliplatin (Eloxatinâ) in Patients With Untreated...” NCT00177307 ↗
Known as JM-83 ChEMBL registry synonym — accepted as the source's own label CHEMBL414804 ↗
Known as l-OHP “The treatment schedule comprised S-1 40-60 mg bid and leucovorin (LV) 25 mg bid for one week and 2 hour drip infusion of oxaliplatin (L-OHP) 85 mg/m2 on day 1, 1 week off,...” PMID 26158159 ↗ Jun 2014
8

“To determine the maximum tolerated dose (MTD) and the dose-limiting toxicities (DLTs) of docetaxel in combination with oxaliplatin (L-OHP) as first-line treatment” PMID 12680184 ↗ Jan 2003

“Meanwhile, oxaliplatin (l-OHP), an alkylating diaminocyclohexane platinum derivate, has been noted to display a marked cytotoxic synergism” NCT01470443 ↗

“Oxaliplatin (L-OHP) 130 mg/m², IV infusion over 2 hours on Day 1” NCT07268677 ↗

“Oxaliplatin (L-OHP)” NCT02497157 ↗

“L-OHP” NCT01212822 ↗

NCT01836653 ↗

NCT01834014 ↗

NCT02280070 ↗

Known as LIOX “5 - 7 LIOX (liver isolation oxaliplatin) intra-arterial infusions over 8 weeks + capecitabine” NCT04701281 ↗
Known as MBP-426 (LIPOSOMAL OXALIPLATIN) ChEMBL registry synonym — accepted as the source's own label CHEMBL414804 ↗
Known as NSC 266046 “Oxaliplatin (NSC 266046) in Combination With 5-Fluorouracil and Leucovorin (FOLFOX4) for Patients Who Have Not Received Prior Chemotherapy for Advanced Colorectal Cancer” NCT00039611 ↗
1

“Oxaliplatin (NSC 266046)” NCT00058149 ↗

Known as OHP “using oxaliplatin (OHP) and endostatin in patients with inoperable esophageal squamous cell carcinoma (ESCC).” PMID 30850562 ↗ Mar 2019
1

“using paclitaxel (PTX) plus oxaliplatin (OHP)” NCT02607982 ↗

Known as Orectalip “Safety of Orectalip® (Oxaliplatin) as Adjuvant Treatment for High-risk Stage-Ⅱ Colorectal Cancer” NCT02284529 ↗
Known as OXA “Oxaliplatin (OXA), a third-generation platinum-based anticancer drug, has better efficacy and lower toxicity than cisplatin and carboplatin.” NCT06856447 ↗
10

“Clinical activity of several regimens containing oxaliplatin (OXA) in advanced HCC had been demonstrated in phase II studies.” NCT02452853 ↗

“Clinical activity of several regimens containing oxaliplatin (OXA) in advanced HCC had been demonstrated in phase II studies.” NCT02426450 ↗

“For grade I-III hypersensitivity to oxaliplatin, oxa 0.01 mg/ml, 0.1 mg/ml and 5 mg/ml were used in sequence for skin test.” NCT05922358 ↗

“Patients are planned to receive the SIRIOX regimen including Oxaliplatin (OXA, 85 mg/m2; d1,d15) of every cycle.” NCT03403101 ↗

“oxaliplatin (OXA) 120 mg/sm, cisplatin (CDDP) 10.5 mg/sm and doxorubicin (DXR) 2.1 mg/sm.” PMID 34070561 ↗ May 2021

“Oxaliplatin (OXA) : 130mg/m2, intravenous infusion, d1, infusion more than 2 hours.” NCT04792515 ↗

“FOLFOX4(infusional fluorouracil [FU], leucovorin [LV], and oxaliplatin [OXA]).” NCT04521491 ↗

“oxaliplatin (OXA), levofolinate calcium (l-LV), 5-FU, panitumumab” NCT02337946 ↗

“oxaliplatin (OXA), levofolinate calcium (l-LV), 5-FU, panitumumab” NCT02394795 ↗

“Intraperitoneal (IP) OXAliplatin (OXA)” NCT02866903 ↗

Known as OXAL “A Phase II Study Of Oxaliplatin (OXAL), 5-Fluorouracil (5-FU), Leucovorin (CF), and Cetuximab (C225) For Patients With Unresectable Hepatic Metastases From Metastatic...” NCT00056030 ↗
4

“A Phase II Study of Oxaliplatin (OXAL), 5-Fluorouracil (5-FU), and Leucovorin (CF) in Patients With Metastatic Colorectal Carcinoma Previously Treated With Irinotecan (CPT-11)” NCT00016978 ↗

“In vitro synergy between Oxal (oxaliplatin) and CPT-11 (irinotecan) has been reported.” PMID 12196376 ↗ Sep 2002

“systemic oxaliplatin (Oxal) combinations plus hepatic arterial infusion (HAI)” PMID 16009951 ↗ Jul 2005

“Drug: Oxaliplatin (OXAL)” NCT02008656 ↗

Known as Oxali “The drugs that will be given by vein are OXALIPLATIN ("Oxali") plus 5-FLUOROURACIL and LEUCOVORIN ("5FU" and "LV").” NCT00059930 ↗
Known as Oxaliplatin (Eloxatin) “Oxaliplatin (Eloxatin)” NCT02178709 ↗
7

“Oxaliplatin (Eloxatin)” NCT01516216 ↗

“Oxaliplatin (Eloxatin)” NCT00659269 ↗

“Oxaliplatin (Eloxatin)” NCT01571024 ↗

“Oxaliplatin (Eloxatin)” NCT00923637 ↗

“Oxaliplatin (Eloxatin)” NCT01749956 ↗

“Oxaliplatin: Eloxatin” NCT01932580 ↗

“Oxaliplatin: Eloxatin” NCT00463840 ↗

Known as Oxaliplatin (Eloxatin○R, company: Sanofi-Avantis “Oxaliplatin (Eloxatin○R, company: Sanofi-Avantis” NCT01558011 ↗
Known as Oxaliplatin (L-OHP, Eloxatin, Sanofi-Synthelabo) “Oxaliplatin (L-OHP, Eloxatin®, Sanofi-Synthelabo)” NCT00153998 ↗
Known as oxaliplatin (ox) “oxaliplatin (ox)” NCT04617457 ↗
Known as oxaliplatin (Oxalip, TTY Biopharm, TW) “oxaliplatin (Oxalip, TTY Biopharm, TW)” NCT04999332 ↗
Known as Oxaliplatin Accord “Oxaliplatin (chemical name: L01XA03; trade name: Oxaliplatin Accord; formulation: concentrate for solution for injection)” NCT07472868 ↗
Known as Oxaliplatin component of folfox ChEMBL registry synonym — accepted as the source's own label CHEMBL414804 ↗
Known as Oxaliplatin component of xelox ChEMBL registry synonym — accepted as the source's own label CHEMBL414804 ↗
Known as Oxaliplatin injection “Drug: Oxaliplatin injection” NCT05799820 ↗