Preoperative Chemoradiotherapy Combined With Consolidation or Induction NALIRIFOX in Rectal Cancer.

Recruiting 68 enrolled Peking University Cancer Hospital & Institute CSPC Ouyi Pharmaceutical Co., Ltd. · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

The Efficacy and Safety of Long-Course Preoperative Chemoradiotherapy Combined with Consolidation or Induction NALIRIFOX Chemotherapy in the Treatment of Locally Advanced Rectal Cancer: A Prospective, Multicenter, Phase II Study.

Timeline

Start: 2025-04-01
Primary completion: 2026-10-31
Completion: 2027-10-31

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Irinotecan	Small molecule	50 mg/m2	Intravenous
Subject	Oxaliplatin	Small molecule	60 mg/m2	Intravenous
Subject	fluorouracil	Small molecule	2400 mg/m2	Intravenous

Indications

No indication recorded.