drugset / Trial / NCT07167446

Neuroprotective Potential of Cannabidiol (CBD) in Preventing Oxaliplatin (Ox)-Induced Neuropathy

NCT07167446

RandomizedParallel-groupOpen-labelSupportive care

Summary

This is a pilot, prospective, randomized study evaluating the feasibility and acceptability of incorporating hemp-derived cannabidiol (CBD) supplementation to prevent oxaliplatin-induced peripheral neuropathy (OIPN) in patients receiving oxaliplatin-based chemotherapy for colorectal cancer (CRC). Participants will be randomized to receive either CBD capsules in addition to standard therapy or standard therapy alone.

Timeline

Start
2025-10-14
Primary completion
2027-09-05
Completion
2028-09-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Cannabidiol Other / unclassified 150 mg Oral
Background Oxaliplatin Small molecule