Drugs / VVZ-149
last change Nov 2022 re-read 2 minutes ago

VVZ-149

Small molecule

Developed for
neuropathy, painful · radiculopathy · sciatica
Investigated by
Vivozon, Inc. · Brigham and Women's Hospital · Vivozon Pharmaceutical Inc.

Trials 13 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT04415645 Feb → Mar 2020 Vivozon, Inc. Completed No outcome recorded
Phase 1 NCT02644421 Nov 2015 → Jul 2017 radiculopathy, sciatica Brigham and Women's Hospital Completed No outcome recorded
Phase 1 NCT02333318 Jul → Sep 2014 Vivozon, Inc. Completed No outcome recorded
Phase 1 NCT01905410 Jul 2013 → Mar 2014 Vivozon, Inc. Completed No outcome recorded
Phase 26 trials
Phase 2 NCT03997812 May → Aug 2019 neuropathy, painful Vivozon, Inc. Completed No outcome recorded
Phase 2 NCT03347266 Dec 2017 → Jul 2018 Vivozon, Inc. Completed No outcome recorded
Phase 2 NCT02992041 Dec 2016 → Apr 2018 Vivozon, Inc. Completed No outcome recorded
Phase 2 NCT02844725 Jun 2016 → Feb 2017 Vivozon, Inc. Completed No outcome recorded
Phase 2 NCT02489526 Sep 2015 → Aug 2016 Vivozon, Inc. Completed No outcome recorded
Phase 2 NCT02522598 Aug 2015 → Feb 2016 Vivozon, Inc. Completed No outcome recorded
Phase 33 trials
Phase 3 NCT05764525 Jul 2021 → Nov 2022 neuropathy, painful Vivozon Pharmaceutical Inc. Completed No outcome recorded
Phase 3 NCT04430088 Jun → Dec 2020 neuropathy, painful Vivozon, Inc. Unknown No outcome recorded
Phase 3 NCT03997838 May → Aug 2019 neuropathy, painful Vivozon, Inc. Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 14 sources stand behind the page.

FieldValueCited text
Known as VVZ-149 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02333318
12

NCT04415645

NCT02992041

NCT02844725

NCT02522598

NCT03997838

NCT02644421

NCT02489526

NCT05764525

NCT04430088

NCT03347266

NCT01905410

NCT03997812

Known as VVZ-149 Injection “Drug: VVZ-149 InjectionNCT01905410
Known as VVZ-149 Injections “The purpose of this phase 3 study is to evaluate the efficacy and safety of an analgesic drug candidate, VVZ-149 Injections for treating post-operative pain following abdominoplasty.” NCT03997838
1

“Drug: VVZ-149 InjectionsNCT04430088

Action Inhibit “VVZ-149 is a novel analgesic drug candidate that shows a potential analgesic activity inhibiting GlyT2 and 5HT2A simultaneously.” NCT01905410
Modality Small molecule “VVZ-149 is a small moleculePMID 34794108 Nov 2021
Route Intravenous “will be given by intravenous infusion for 4 hours.” NCT01905410