drugset / Trial / NCT02333318
A Single Ascending Dose Escalation to Investigate Safety and PK of VVZ-149 Injection in Healthy Older Male Volunteers
RandomizedParallel-groupTriple-blindHealth-services research
Summary
The objective of this study is to investigate the safety, tolerability and pharmacokinetics (PK) of VVZ-149 injection after a single dose or loading/maintenance dose in healthy older male volunteers.
Timeline
- Start
- 2014-07
- Primary completion
- 2014-09
- Completion
- 2014-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | VVZ-149 | Small molecule | 0.55 mg/kg | Intravenous |
| Subject | VVZ-149 | Small molecule | 1.1 mg/kg | Intravenous |
| Subject | VVZ-149 | Small molecule | 2.5 mg/kg | Intravenous |
| Subject | VVZ-149 | Small molecule | 5 mg/kg | Intravenous |
Indications
No indication recorded.