Drugs / AS03

Trials 21 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 17 trials
Phase 1 NCT05561673 Oct 2022 → Nov 2024 hepatitis B virus infection GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT03275389 Sep 2017 → Mar 2020 influenza GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT03014310 Jan 2017 → Dec 2018 avian influenza National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1 NCT02957656 Dec 2016 → Jun 2018 National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1 NCT02624219 Aug 2016 → Jan 2018 avian influenza National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1 NCT01573312 May 2012 → Jan 2014 influenza National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1 NCT01317758 May 2011 → Sep 2012 influenza National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1/24 trials
Phase 1/2 NCT04959344 Jul 2021 → Sep 2022 Klebsiella infectious disease LimmaTech Biologics AG Completed No outcome recorded
Phase 1/2 NCT04750343 Feb → Jul 2021 SK Bioscience Co., Ltd. Unknown No outcome recorded
Phase 1/2 NCT04622592 Nov 2020 → Apr 2022 influenza Medicago Completed No outcome recorded
Phase 1/2 NCT01578317 Mar 2012 → Jan 2016 influenza National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 210 trials
Phase 2 NCT03738241 Dec 2018 → Jun 2020 avian influenza National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT03589807 Aug 2018 → Jun 2020 avian influenza National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT03497845 Mar 2018 → Nov 2019 avian influenza Biomedical Advanced Research and Development Authority Completed No outcome recorded
Phase 2 NCT03312231 Feb 2018 → Sep 2019 avian influenza National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT03283319 Sep → Dec 2017 influenza Biomedical Advanced Research and Development Authority Completed No outcome recorded
Phase 2 NCT02921997 Nov 2016 → Mar 2017 avian influenza, swine influenza National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT01942265 Sep 2013 → Jan 2015 influenza National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT01910519 Jul 2013 → Feb 2015 avian influenza National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT00963157 Sep 2009 → Dec 2010 influenza National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT00964951 ? → Nov 2010 influenza National Institute of Allergy and Infectious Diseases (NIAID) Withdrawn No outcome recorded
Also used as a comparator or background therapy in 3 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT04405908 Comparator Jun 2020 → Oct 2021 COVID-19 Clover Biopharmaceuticals AUS Pty Completed No outcome recorded
Phase 22 trials
Phase 2 NCT05289037 Background Mar 2022 → Nov 2023 COVID-19 National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 2 NCT03318315 Background Feb 2018 → Jul 2019 avian influenza National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 24 sources stand behind the page.

FieldValueCited text
Known as AS03 “Participants received one intramuscular (IM) injection (total volume 0.7 mL) of 15 μg/strain of the Quadrivalent virus-like particle (VLP) Influenza Vaccine adjuvanted with...” NCT04622592
19

“intramuscular subvirion inactivated monovalent influenza A/H5N1 (HA of A/Indonesia/05/2005) virus vaccine manufactured by Sanofi Pasteur administered at 3.75 mcg per dose given...” NCT01573312

NCT00963157

NCT03312231

NCT02624219

NCT05289037

NCT04405908

NCT00964951

NCT01910519

NCT05561673

NCT03014310

NCT03318315

NCT03283319

NCT01942265

NCT01578317

NCT03738241

NCT04750343

NCT02921997

NCT04959344

NCT03589807

Known as AS03 Adjuvant ClinicalTrials.gov intervention name — accepted as the source's own label NCT01317758
2

NCT02957656

NCT03497845

Known as D-SUIV cH8/1N1+AS03 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03275389
Modality Other / unclassified “Adjuvant/diluent manufactured by GlaxoSmithKline (GSK)” NCT01317758
Route Intramuscular “Ten subjects will be vaccinated with 3.75 micrograms(mcg) of H5N1 hemagglutinin plus AS03 given intramuscularly in two doses 28 days apart.” NCT01573312