Clorazepate

also known as 4306 CB · 4311 CB · AB 35616 · ABBOTT-35616 · CB 4306 · Clorazepate dipotassique · Clorazepate Dipotassium · Clorazepate dipotassium civ · +10 more

Small molecule

Developed for: migraine with aura · migraine without aura
Investigated by: Assistance Publique - Hôpitaux de Paris

Regulatory milestones approvals, filings & regulatory actions · 2 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Label expansion	US (FDA)	TRANXENE	—	1981-01-29	fda.gov ↗
Approved	US (FDA)	TRANXENE	—	1972-06-23	fda.gov ↗

Trials 1 · a red edge is where a trial was stopped

today

US approved 1972

NCT04726592 · Ph 3

1971197219731974197519761977197819791980198119821983198419851986198719881989199019911992199319941995199619971998199920002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 3	NCT04726592	Jul 2021 → Apr 2024	migraine with aura, migraine without aura	Assistance Publique - Hôpitaux de Paris	Terminated	No outcome recorded

Also used as a comparator or background therapy in 1 trial

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 4	NCT01305707 Comparator	Jul 2009 → Jul 2014	major depressive disorder	Hospital Universitari de Bellvitge	Terminated	No outcome recorded

Evidence & citations 21 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

Field	Value	Cited text
Known as	Clorazepate	“- Clorazepate 5-50 mg/d. N05BA05” NCT01305707 ↗
Known as	4306 CB	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	4311 CB	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	AB 35616	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	ABBOTT-35616	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	CB 4306	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	Clorazepate dipotassique	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	Clorazepate Dipotassium	ClinicalTrials.gov intervention name — accepted as the source's own label NCT04726592 ↗
Known as	Clorazepate dipotassium civ	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	Clorazepate potassium	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	Clorazepato de dipotasio	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	Clorazepic acid dipotassium salt	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	CM 4306	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	Dipotassium clorazepate	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	Gen-xene	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	Potassium clorazepate	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	TR 19119	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	Tranxene	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Known as	Tranxene sd	ChEMBL registry synonym — accepted as the source's own label CHEMBL1213252 ↗
Modality	Small molecule	— CHEMBL1213252 ↗
Route	Intravenous	“Clorazepate Dipotassium : 20 mg intravenous injection” NCT04726592 ↗