Drugs / Fluzone HD
Fluzone HD
Trials 5
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT05163847 | Jun → Nov 2022 | — | FluGen Inc | Completed | No outcome recorded |
| Phase 22 trials · 1 met primary | ||||||
| Phase 2 | NCT06431607 | May → Dec 2024 | influenza | GlaxoSmithKline | Completed | Met primary |
| Phase 2 | NCT03658629 | Sep 2018 → Apr 2019 | influenza | Novavax | Terminated | No outcome recorded |
| Phase 2/31 trial · 1 met primary | ||||||
| Phase 2/3 | NCT03699839 | Oct 2018 → Aug 2020 | disease related to solid organ transplantation, influenza | Oriol Manuel | Completed | Met primary |
| Phase 31 trial | ||||||
| Phase 3 | NCT06060457 | Sep 2023 → Jun 2024 | respiratory syncytial virus infectious disease | ModernaTX, Inc. | Completed | Mixed |
| Comparator or background therapy5 trials | ||||||
| Phase 1/2 | NCT03293498 Comparator | Sep 2017 → Mar 2018 | influenza | Novavax | Completed | No outcome recorded |
| Phase 3 | NCT05827978 Comparator | Apr 2023 → Jun 2024 | influenza | ModernaTX, Inc. | Completed | Met primary |
| Phase 4 | NCT03694808 Comparator | Sep 2018 → Jan 2023 | influenza | David H. Canaday | Completed | No outcome recorded |
| Phase 4 | NCT03068949 Comparator | Oct 2015 → Jun 2020 | influenza | University of Rochester | Completed | No outcome recorded |
| — | NCT02872311 Comparator | Sep 2016 → Apr 2018 | — | Marshfield Clinic Research Foundation | Completed | No outcome recorded |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 12 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Fluzone HD | “The experimental intervention consists in an intramuscular injection of a MF59-adjuvanted trivalent inactivated influenza vaccine containing 15 µg of antigen per strain...” NCT03699839 ↗9“Licensed and FDA approved Fluzone HD vaccine to be administered to study participants” NCT02872311 ↗ “Fluzone HD” NCT05827978 ↗ |
| Known as | Fluzone High-Dose Quadrivalent | “licensed inactivated influenza vaccine (Fluzone High-Dose Quadrivalent; hereafter referred to as Fluzone HD)” PMID 39004096 ↗ Jul 2024 |
| Known as | HD-IIV3 | “adjuvanted flu vaccine (aTIV, FLUAD) vs high-dose flu vaccine (HD-IIV3, FLUZONE HD)” PMID 40373825 ↗ May 2025 |
| Modality | Vaccine | “Licensed and FDA approved Fluzone HD vaccine to be administered to study participants” NCT02872311 ↗ |
| Route | Intramuscular | “given intramuscularly” NCT03068949 ↗ |