drugset

drugset / Trial / NCT03068949

Comparison of Three Licensed Influenza Vaccines

NCT03068949 ↗

Phase 4 Completed 413 enrolled University of Rochester National Institutes of Health (NIH) · collab

RandomizedParallel-groupDouble-blindBasic science

Summary

This study will evaluate in detail the way that the immune system responds to three different kinds of flu shots that are licensed in the United States.

Timeline

Start: 2015-10-28
Primary completion: 2020-06-30
Completion: 2021-06-30

Publications

Gouma S, Zost SJ, Parkhouse K, Branche A, Topham DJ, Cobey S, Hensley SE. Comparison of Human H3N2 Antibody Responses Elicited by Egg-Based, Cell-Based, and Recombinant Protein-Based Influenza Vaccines During the 2017-2018 Season. Clin Infect Dis. 2020 Sep 12;71(6):1447-1453. doi: 10.1093/cid/ciz996.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Flublok	Vaccine	0.5 ml	Intramuscular
Comparator	Flucelvax	Vaccine	0.5 ml	Intramuscular
Comparator	Fluzone	Vaccine	0.5 ml	Intramuscular
Comparator	Fluzone HD	Vaccine	0.5 ml	Intramuscular

Indications