Drugs / triamterene
triamterene
also known as
Dyrenium · Dytac · NSC-639359 · NSC-77625 · SK&F 8542 · SK-8542 · Triamterene component of dyazide · Triamterene component of maxzide · +1 more
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | DYRENIUM | — | 1964-08-10 | fda.gov ↗ |
Trials 1 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 3 | NCT00000525 | Jul 1986 → Sep 1989 | cardiac arrest, hypertensive disorder, sudden arrhythmia death syndrome | University of California, San Francisco | Completed | No outcome recorded |
Also used as a comparator or background therapy in 3 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 41 trial | ||||||
| Phase 4 | NCT02522650 Comparator | Jul 2013 → Oct 2021 | proteinuria | Georgetown University | Unknown | No outcome recorded |
| Phase not applicable2 trials | ||||||
| — | NCT01661777 Comparator | Aug 2012 → Aug 2013 | endolymphatic hydrops, eustachian tube disorder | Vanderbilt University | Withdrawn | No outcome recorded |
| — | NCT00684489 Comparator | Sep 2003 → Mar 2005 | essential hypertension | Medical University of South Carolina | Completed | No outcome recorded |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 5 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | triamterene | “The mainstays of management of endolymphatic hydrops are a low sodium diet and diuretic treatment (hydrochlorothiazide/triamterene).” NCT01661777 ↗3“metolazone, bumetanide, furosemide, torsemide, amiloride, triamterene, eplerenone, spironolactone” NCT00684489 ↗ |
| Known as | Dyrenium | ChEMBL registry synonym — accepted as the source's own label CHEMBL585 ↗ |
| Known as | Dytac | ChEMBL registry synonym — accepted as the source's own label CHEMBL585 ↗ |
| Known as | NSC-639359 | ChEMBL registry synonym — accepted as the source's own label CHEMBL585 ↗ |
| Known as | NSC-77625 | ChEMBL registry synonym — accepted as the source's own label CHEMBL585 ↗ |
| Known as | SK&F 8542 | ChEMBL registry synonym — accepted as the source's own label CHEMBL585 ↗ |
| Known as | SK-8542 | ChEMBL registry synonym — accepted as the source's own label CHEMBL585 ↗ |
| Known as | Triamterene component of dyazide | ChEMBL registry synonym — accepted as the source's own label CHEMBL585 ↗ |
| Known as | Triamterene component of maxzide | ChEMBL registry synonym — accepted as the source's own label CHEMBL585 ↗ |
| Known as | Triamtereno | ChEMBL registry synonym — accepted as the source's own label CHEMBL585 ↗ |
| Modality | Small molecule | — CHEMBL585 ↗ |