Drugs / Tenofovir Amibufenamide

Trials 5 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT07295873 Dec 2025 → Jun 2026 overdue fibrotic liver disease Beijing Continent Pharmaceutical Co, Ltd. Not yet recruiting No outcome recorded
Phase 21 trial
Phase 2 NCT05382351 May 2022 → Apr 2024 chronic hepatitis B virus infection Sun Yat-sen University Unknown No outcome recorded
Phase 41 trial
Phase 4 NCT06743438 Mar 2022 → Jun 2024 overdue chronic hepatitis B virus infection Jiangsu Hansoh Pharmaceutical Co., Ltd. Active not recruiting No outcome recorded
Phase not applicable2 trials
NCT05797714 Jun 2022 → Apr 2024 overdue chronic hepatitis B virus infection Ruijin Hospital Active not recruiting No outcome recorded
NCT05398393 Jan 2022 → Jun 2023 chronic hepatitis B virus infection, lip disorder Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Unknown No outcome recorded
Also used as a comparator or background therapy in 2 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT07553767 Background Mar 2026 → Dec 2034 expected chronic hepatitis B virus infection, hepatocellular carcinoma Ningbo No.2 Hospital Not yet recruiting No outcome recorded
Phase not applicable1 trial
NCT06323681 Comparator Feb 2024 → Feb 2027 expected chronic hepatitis B virus infection Qing XIe Recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as tenofovir amibufenamide “First-line NAs (e.g. Entecavir (ETV), tenofovir disoproxil fumarate (TDF), tenofovir alafenamide fumarate (TAF), tenofovir amibufenamide (TMF)), one tablet a day, take orally,...” NCT06323681
6

Tenofovir amibufenamideNCT07553767

NCT06743438

NCT05398393

NCT07295873

NCT05382351

NCT05797714

Known as HS-10234 “Tenofovir amibufenamide (TMF; codename: HS-10234), another formulation of tenofovir, shared the same ProTide technology as tenofovir alafenamide, which can provide more...” NCT05797714
Known as TMF “First-line NAs (e.g. Entecavir (ETV), tenofovir disoproxil fumarate (TDF), tenofovir alafenamide fumarate (TAF), tenofovir amibufenamide (TMF)), one tablet a day, take orally,...” NCT06323681
4

“Tenofovir amibufenamide (TMF) is a novel prodrug of tenofovir that has been widely used in mainland China for the treatment of chronic hepatitis B (CHB).” NCT06743438

“new drug Tenofovir Amibufenamide(TMF)” NCT05398393

“Drug: Tenofovir Amibufenamide(TMF)” NCT05797714

“Tenofovir Amibufenamide(TMF)” NCT07295873

Route Oral “enofovir amibufenamide orally 25mg once a day with meals” NCT05382351