enamel matrix derivative
Trials 6
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 21 trial | ||||||
| Phase 2 | NCT02135471 | Jun 2009 → Nov 2011 | gingival recession | University of Sao Paulo | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT05418621 | Mar 2021 → Sep 2024 | periodontal disorder | University of Pisa | Unknown | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT06190015 | May 2022 → Jan 2024 | — | University of Belgrade | Unknown | No outcome recorded |
| Phase not applicable3 trials · 1 missed | ||||||
| — | NCT07727655 | Sep 2026 → Mar 2027 expected | tooth disorder | Mansoura University | Recruiting | No outcome recorded |
| — | NCT07233733 | Jun 2024 → Mar 2025 | periodontitis | Phạm Đình Thiên Khải | Completed | No outcome recorded |
| — | NCT02195765 | Jun 2002 → Oct 2004 | chronic periodontitis | University of Sao Paulo | Completed | Missed primary |
| Comparator or background therapy1 trial | ||||||
| Phase 4 | NCT04274244 Comparator | Mar 2020 → Sep 2024 | chronic periodontitis | University of Valencia | Completed | No outcome recorded |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 10 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Enamel matrix derivative | “AIM: To compare the effects of 1.8% hyaluronic acid (HA) and enamel matrix derivative (EMD) on periodontal regeneration in patients with periodontal bone defects, using...” PMID 40106008 ↗ Mar 20256“Conditioning of the root surface with 24% EDTA gel for 2 minutes, rinsing, followed by application of enamel matrix derivative (EMD; Emdogain®) to the root surface and into the...” NCT07233733 ↗ “Enamel matrix derivative (EMD) group” NCT06190015 ↗ |
| Known as | EMD | “BACKGROUND: This split-mouth, double-blind randomized controlled trial evaluated radiographic changes in infrabony defects treated with open flap debridement (OFD) or OFD...” PMID 25475143 ↗ Dec 20142“Conditioning of the root surface with 24% EDTA gel for 2 minutes, rinsing, followed by application of enamel matrix derivative (EMD; Emdogain®) to the root surface and into the...” NCT07233733 ↗ “Enamel matrix derivative (EMD) group” NCT06190015 ↗ |
| Known as | Emdogain | “A single application of enamel matrix derivative (EMD, commercially known as Emdogain) will be applied to the extraction socket during immediate dental implant placement in the...” NCT07727655 ↗1“Conditioning of the root surface with 24% EDTA gel for 2 minutes, rinsing, followed by application of enamel matrix derivative (EMD; Emdogain®) to the root surface and into the...” NCT07233733 ↗ |
| Modality | Protein / enzyme biologic | “enamel matrix proteins (EMP)” PMID 20165744 ↗ Feb 2010 |
| Route | Other | “Application of Emdogain® filling the bone defect from the bottom upwards in the active comparator group.” NCT04274244 ↗ |