Praziquantel
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | BILTRICIDE | — | 1982-12-29 | fda.gov ↗ |
Trials 29
Evidence & citations 17 cited values
Every value below carries the sentence it was read from. 53 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | praziquantel | “A randomized controlled trial was used to compare the effectiveness of praziquantel in treating Schistosoma haematobium in Africa using two different sources for the drug,...” PMID 30969960 ↗ Apr 201945“The intervention drugs are standard drugs approved by the World Health Organisation for the preventive treatment of malaria (sulphadoxine-pyrimethamine and amodiaquine),...” NCT06182176 ↗ “Re-assessment by questionnaire, physical examination and sampling for STIs was undertaken 4 weeks later followed by systematic praziquantel treatment to general community,...” NCT00713999 ↗ “Participants aged 4 to 6 years infected with S. mansoni received Racemate Praziquantel tablets (Biltricide®) (600 mg) orally at a dose of 40 mg/kg as a single oral dose after...” NCT03845140 ↗ “Praziquantel (PZQ) is currently the only recommended drug for infection and disease caused by the schistosome species that infects humans” PMID 34106922 ↗ Jun 2021 “Relative Bioavailability of Orally Dispersible Tablet Formulations of Levo- and Racemic Praziquantel: Two Phase I Studies.” PMID 30536632 ↗ Dec 2018 “Praziquantel single dose 40mg/kg will be given for infection with Schistosoma mansoni and Schistosoma haematobium.” NCT05323396 ↗ “Nitazoxanide, Chloroquine, Albendazole, Ivermectin, Mebendazole, Metronidazole, Praziquantel, Levamisole” NCT02366884 ↗ “or 40mg/Kg body weight of Praziquantel as a single oral dose.” NCT01529710 ↗ |
| Known as | Biltricide | “Participants aged 4 to 6 years infected with S. mansoni received Racemate Praziquantel tablets (Biltricide®) (600 mg) orally at a dose of 40 mg/kg as a single oral dose after...” NCT03845140 ↗1“Biltricide (racemate praziquantel) oral tablets” NCT02806232 ↗ |
| Known as | Cesol | ChEMBL registry synonym — accepted as the source's own label CHEMBL976 ↗ |
| Known as | Cestocur | ChEMBL registry synonym — accepted as the source's own label CHEMBL976 ↗ |
| Known as | Cisticid | ChEMBL registry synonym — accepted as the source's own label CHEMBL976 ↗ |
| Known as | Cysticide | “Subjects will receive a single oral dose of current PZQ formulation (Cysticide®) at 40 mg/kg with water, under fed condition in one of the intervention periods.” NCT02271984 ↗ |
| Known as | Distocide | “one received a single standard dose of praziquantel (Distocide® 600 mg, Shin Poong Pharmaceuticals, Seoul, Republic of Korea), 40mg/kg body weight, while the other group...” PMID 23596262 ↗ Apr 20131“Praziquantel (Distocide) 60 mg/kg single oral dose” NCT00403611 ↗ |
| Known as | EMBAY 8440 | ChEMBL registry synonym — accepted as the source's own label CHEMBL976 ↗ |
| Known as | NSC-757285 | ChEMBL registry synonym — accepted as the source's own label CHEMBL976 ↗ |
| Known as | Prazicuantel | ChEMBL registry synonym — accepted as the source's own label CHEMBL976 ↗ |
| Known as | Praziquantel component of broadline | ChEMBL registry synonym — accepted as the source's own label CHEMBL976 ↗ |
| Known as | Praziquantel component of profender | ChEMBL registry synonym — accepted as the source's own label CHEMBL976 ↗ |
| Known as | Praziquantelum | ChEMBL registry synonym — accepted as the source's own label CHEMBL976 ↗ |
| Known as | PZQ | “A longitudinal study was conducted to evaluate the impact of praziquantel (PZQ) for the treatment of Schistosoma mansoni infection among schoolchildren in Al Gunaid in Central Sudan.” PMID 21729382 ↗ Jun 20119“The study was conducted in Djalakorodji, a peri-urban area of Bamako, Mali, using a double blind setup in which As+SMP was compared with praziquantel (PZQ).” PMID 19802383 ↗ Oct 2009 “Racemate Praziquantel (PZQ) (150) mg was administered at a dose of 40 mg/kg in Part 1, Cohort 3 and at a dose of 60 mg/kg in Part 1, Cohort 4.” NCT02806232 ↗ “The exclusive use of praziquantel (PZQ) in mass drug administration programmes may result in the emergence of drug resistance.” PMID 34168029 ↗ Jun 2021 “The purpose of the study is to understand whether the drug praziquantel (PZQ) is safe for the mother and developing baby” NCT00486863 ↗ “Praziquantel (PZQ), 60 mg/kg, administered orally in split dose (30 mg/kg each dose) separated by three hours.” NCT01288872 ↗ “Preventive chemotherapy with praziquantel (PZQ) is the cornerstone of schistosomiasis control.” PMID 32196506 ↗ Mar 2020 “Praziquantel (PZQ), the drug used worldwide for the treatment of schistosomiasis” NCT03640377 ↗ “Praziquantel (PZQ) is a drug used to treat this infection.” NCT02734186 ↗ “Drug: Praziquantel (PZQ)” NCT02144389 ↗ |
| Known as | Racemate Praziquantel | “Biltricide (racemate praziquantel) oral tablets” NCT02806232 ↗ |
| Modality | Small molecule | “Praziquantel is a heterocyclic prazino-isoquinoline derivative with significant activity against both cestodes and trematodes.” NCT00507221 ↗ |
| Route | Oral | “single oral dose” NCT00403611 ↗ |