drugset / Trial / NCT02325713
Relative Bioavailability Trial of Oral Dispersible Praziquantel Tablets in Healthy Volunteers
RandomizedCrossoverOpen-labelTreatment
Summary
This is a phase I, open-label, randomized, 4 period, crossover, single-center trial. The purpose of this trial is to assess the relative bio-availability of racemate Oral Dispersible Tablet praziquantel (ODT-PQZ) (MSC1028703A) 150 milligram (mg) versus the current marketed praziquantel (PZQ) (Cysticide® 500 mg) formulation in healthy male volunteers.
Timeline
- Start
- 2015-01
- Primary completion
- 2015-01
- Completion
- 2015-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Praziquantel | Small molecule | 20 mg/kg | Oral |
| Subject | Praziquantel | Small molecule | 40 mg/kg | Oral |
| Subject | Praziquantel | Small molecule | 60 mg/kg | Oral |
Indications
No indication recorded.