Drugs / COH29
last change Nov 2018 re-read 3 minutes ago

COH29

Small molecule

Developed for
cancer of unknown primary site
Investigated by
City of Hope Medical Center · National Cancer Institute (NCI)

Trials 1

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02112565 Jun 2016 → Nov 2018 overdue cancer of unknown primary site City of Hope Medical Center Active not recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as COH29 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02112565 ↗
Known as City of Hope 29 “This phase I trial studies the side effects and best dose of RNR Inhibitor City of Hope 29 (COH29) in treating patients with solid tumors that are refractory to standard...” NCT02112565 ↗
Known as Rnr inhibitor coh29 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297421 ↗
Action Inhibit “COH29 may inhibit an enzyme called ribonucleotide reductase” NCT02112565 ↗
Modality Small molecule — CHEMBL4297421 ↗
Route Oral “COH29 orally (PO)” NCT02112565 ↗