drugset / Trial / NCT02112565

RNR Inhibitor COH29 in Treating Patients With Solid Tumors That Are Refractory to Standard Therapy or For Which No Standard Therapy Exists

NCT02112565 ↗

NaSingle-groupOpen-labelTreatment

Summary

This phase I trial studies the side effects and best dose of RNR Inhibitor City of Hope 29 (COH29) in treating patients with solid tumors that are refractory to standard therapy or for which no standard therapy exists. COH29 may inhibit an enzyme called ribonucleotide reductase and may interfere with the ability of tumor cells to grow.

Timeline

Start
2016-06-13
Primary completion
2018-11-23
Completion
2027-05-12

Drugs

EvaluationDrugModalityDoseRoute
Subject COH29 Small molecule — Oral