Drugs / Hetrombopag Olamine
Hetrombopag Olamine
also known as
Hetrombopag diolamine · Hetrombopag ethanolamine · Rafutrombopag olamine · SHR-8735 OLAMINE
targets MPL via activation
Trials 4 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials | ||||||
| Phase 2 | NCT06478537 | Jun 2024 → Jun 2027 expected | thrombocytopenia due to immune destruction | Peking Union Medical College Hospital | Recruiting | No outcome recorded |
| Phase 2 | NCT05944211 | Jul 2023 → Jul 2026 overdue | thrombocytopenia | RenJi Hospital | Not yet recruiting | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT07286032 | Apr 2026 → Dec 2028 expected | thrombocytopenia | Jiangsu HengRui Medicine Co., Ltd. | Recruiting | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT05575986 | Oct 2022 → Oct 2023 | digestive system cancer, thrombocytopenia | Huazhong University of Science and Technology | Unknown | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1 | NCT03603132 Comparator | Jul → Aug 2018 | autoimmune thrombocytopenia | Jiangsu HengRui Medicine Co., Ltd. | Completed | No outcome recorded |
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Hetrombopag Olamine | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03603132 ↗ |
| Known as | Hetrombopag diolamine | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297764 ↗ |
| Known as | Hetrombopag ethanolamine | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297764 ↗ |
| Known as | Rafutrombopag olamine | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297764 ↗ |
| Known as | SHR-8735 OLAMINE | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297764 ↗ |
| Action | Activate | “Thrombopoietin receptor agonist” CHEMBL4297764 ↗ |
| Route | Oral | “single oral dose” NCT03603132 ↗ |
| Target | MPL | “Thrombopoietin receptor agonist” CHEMBL4297764 ↗ |