drugset / Trial / NCT06478537

TPO-RA Treatment on Immune Tolerance Induction of ITP Patients With Sustained Platelet Recovery After Treatment Termination

NCT06478537

Phase 2 Recruiting 56 enrolled Peking Union Medical College Hospital
NaSingle-groupOpen-labelTreatment

Summary

The aim of this study was to observe whether maintaining a high level of platelet count after TPO-RA in patients with primary immune thrombocytopenia (ITP) can induce immune tolerance, develop immune balance in ITP patients, and enable patients to achieve a sustained response (SRoT) after TPO-RA discontinuation.

Timeline

Start
2024-06-20
Primary completion
2027-06-20
Completion
2027-06-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Hetrombopag Olamine Unknown 2.5 mg
Subject Hetrombopag Olamine Unknown 7.5 mg
Background Aspirin Small molecule 100 mg