Drugs / IDREBORMILAST
last change Feb 2025 re-read 2 minutes ago

IDREBORMILAST

also known as PF-07038124

Small molecule

Developed for
atopic eczema · psoriasis · rosacea · seborrheic dermatitis · vitiligo
Investigated by
Pfizer · Icahn School of Medicine at Mount Sinai · University of Colorado, Denver

Trials 6 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT04863417 Jun → Sep 2021 Pfizer Completed No outcome recorded
Phase 1 NCT04135560 Oct 2019 → Apr 2020 atopic eczema Pfizer Completed No outcome recorded
Phase 24 trials
Phase 2 NCT06013371 Jul 2023 → Feb 2025 rosacea, seborrheic dermatitis Icahn School of Medicine at Mount Sinai Terminated No outcome recorded
Phase 2 NCT05375955 Sep 2022 → Jul 2023 atopic eczema, psoriasis Pfizer Completed No outcome recorded
Phase 2 NCT05298033 Sep 2022 → Apr 2024 vitiligo University of Colorado, Denver Completed No outcome recorded
Phase 2 NCT04664153 Dec 2020 → Aug 2021 atopic eczema, psoriasis Pfizer Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as IDREBORMILAST ChEMBL registry synonym — accepted as the source's own label CHEMBL6056273
Known as PF-07038124 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04135560
5

NCT04863417

NCT05375955

NCT04664153

NCT06013371

NCT05298033

Action Inhibit “the topical phosphodiesterase 4 inhibitor PF-07038124” PMID 38117526 Feb 2024
Modality Small molecule CHEMBL6056273
Route Topical “PF-07038124 ointment and vehicle (placebo) in Part A following multiple-doses applied topically to healthy participants” NCT04135560