drugset / Trial / NCT05298033

Study of Efficacy, Safety and Tolerability of Crisaborole and PF-07038124 With and Without NBUVB in Vitiligo

NCT05298033

Phase 2 Completed 32 enrolled University of Colorado, Denver Pfizer · collab
RandomizedFactorialQuadruple-blindTreatment

Summary

This is a phase 2A clinical trial designed to test the pro-melanogenic and anti-inflammatory role of phosphodiesterase-4 inhibitors (PDE4i), alone and in combination with active narrow band UVB (NBUVB), in vitiligo lesions. This is a double-blind, randomized controlled trial (RCT) with six study arms. The goal is for 64 participants to be recruited and complete the study.

Timeline

Start
2022-09-07
Primary completion
2024-04-30
Completion
2024-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Crisaborole Small molecule 2 % Topical
Subject IDREBORMILAST Small molecule 0.01 % Topical

Indications