Drugs / Domperidone
last change May 2026 re-read 2 minutes ago

Domperidone

Developed for
gastroparesis · gastroesophageal reflux disease · dyspepsia · constipation disorder · esophagitis · idiopathic gastroparesis · Parkinson disease · gastroenteritis
+6 more · orthostatic hypotension · pulmonary immaturity · relapsing-remitting multiple sclerosis · secondary progressive multiple sclerosis · systemic sclerosis · type 1 diabetes mellitus
Investigated by
Alberta Innovates Health Solutions · Janssen Research & Development, LLC · Neutec Ar-Ge San ve Tic A.Ş · University of Calgary · Yale University · Allegiance Health
+38 more · Arnold, George, M.D. · Canadian Nurses Foundation (CNF) · Carle Physician Group · Children's Hospital of Fudan University · Dalhousie University · David J. Lederer, M.D. · Dinara Zhumanbayeva · Eastern Regional Medical Center · Eurofarma Laboratorios S.A. · Guangdong Provincial Maternal and Child Health Hospital · Guangzhou Panyu Central Hospital · Hamilton Health Sciences Corporation · IWK Health Centre · Irish Research Council · Janssen-Cilag International NV · Jose Cocjin · KU Leuven · Khon Kaen University · M.D. Anderson Cancer Center · Mansoura University Children Hospital · Maternal and Child Health Hospital of Foshan · Nanfang Hospital, Southern Medical University · Nantes University Hospital · National Cancer Institute (NCI) · Palo Alto Medical Foundation · Prasanna K Kapavarapu · RenJi Hospital · Ron Schey · Royal Brisbane and Women's Hospital · Scott Gabbard, MD · Shen-Zhen City Maternity and Child Healthcare Hospital · The Physicians' Services Incorporated Foundation · University Health Network, Toronto · University Hospital, Rouen · University of Limerick · Wake Forest University Health Sciences · Xian-Janssen Pharmaceutical Ltd. · Yehudith Assouline-Dayan

Trials 38 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials
Phase 1 NCT02816853 May → Aug 2016 Janssen Research & Development, LLC Completed No outcome recorded
Phase 1 NCT01643889 Jul → Nov 2012 Janssen Research & Development, LLC Completed No outcome recorded
Phase 1 NCT00103597 Jan → Sep 2005 Parkinson disease, multiple system atrophy, orthostatic hypotension Royal Brisbane and Women's Hospital Completed No outcome recorded
Phase 26 trials
Phase 2 NCT02493049 Aug 2015 → Feb 2019 relapsing-remitting multiple sclerosis University of Calgary Completed No outcome recorded
Phase 2 NCT02308137 Feb 2015 → Jan 2020 secondary progressive multiple sclerosis University of Calgary Completed No outcome recorded
Phase 2 NCT00760461 Oct 2008 → Jul 2011 gastroparesis Yale University Terminated No outcome recorded
Phase 2 NCT00284024 Sep 2006 → Sep 2007 Hamilton Health Sciences Corporation Terminated No outcome recorded
Phase 2 NCT00305331 Mar 2006 → Jul 2008 Parkinson disease University Health Network, Toronto Terminated No outcome recorded
Phase 2 NCT00238056 pulmonary immaturity Nantes University Hospital Completed No outcome recorded
Phase 2/32 trials
Phase 2/3 NCT04802785 Jun → Jul 2021 Dinara Zhumanbayeva Unknown No outcome recorded
Phase 2/3 NCT00308334 Oct 2003 → Dec 2007 IWK Health Centre Completed No outcome recorded
Phase 36 trials
Phase 3 NCT06695962 Mar 2026 → Jun 2029 expected type 1 diabetes mellitus University Hospital, Rouen Not yet recruiting No outcome recorded
Phase 3 NCT02699385 Dec 2015 → Aug 2017 gastroenteritis Janssen-Cilag International NV Terminated No outcome recorded
Phase 3 NCT01710462 Aug 2013 → ? gastroesophageal reflux disease Eurofarma Laboratorios S.A. Withdrawn No outcome recorded
Phase 3 NCT01878526 Jun 2013 → Aug 2015 gastroesophageal reflux disease, systemic sclerosis Khon Kaen University Completed No outcome recorded
Phase 3 NCT01696734 Oct 2012 → Oct 2027 expected dyspepsia, esophagitis, gastroesophageal reflux disease, gastroparesis M.D. Anderson Cancer Center Recruiting No outcome recorded
Phase 3 NCT01378884 Mar 2010 → Mar 2012 gastroparesis Allegiance Health Withdrawn No outcome recorded
Phase 46 trials
Phase 4 NCT04583111 Mar 2020 → Mar 2022 RenJi Hospital Unknown No outcome recorded
Phase 4 NCT03617016 Aug 2018 → Jul 2020 dyspepsia Xian-Janssen Pharmaceutical Ltd. Completed No outcome recorded
Phase 4 NCT03355170 Mar → Dec 2018 gastroesophageal reflux disease, heart disorder Neutec Ar-Ge San ve Tic A.Ş Withdrawn No outcome recorded
Phase 4 NCT02980250 Nov 2015 → May 2017 stomach disorder Nanfang Hospital, Southern Medical University Completed No outcome recorded
Phase 4 NCT02958046 Jan 2014 → May 2015 gastroesophageal reflux disease Neutec Ar-Ge San ve Tic A.Ş Completed No outcome recorded
Phase 4 NCT02685436 Mar 2013 → May 2015 gastroesophageal reflux disease Mansoura University Children Hospital Completed No outcome recorded
Phase not applicable8 trials
NCT03662113 Nov 2017 → Nov 2018 Children's Hospital of Fudan University Completed No outcome recorded
NCT04699591 Apr 2013 → Dec 2035 expected gastroesophageal reflux disease, gastroparesis Jose Cocjin Recruiting No outcome recorded
NCT01780909 Feb → Dec 2013 KU Leuven Unknown No outcome recorded
NCT01711918 Jul 2012 → Apr 2014 idiopathic gastroparesis Ron Schey Completed No outcome recorded
NCT00777439 Oct 2008 → Jan 2017 gastroparesis Arnold, George, M.D. Unknown No outcome recorded
NCT00761254 Aug 2008 → Sep 2012 constipation disorder, dyspepsia, esophagitis, gastroesophageal reflux disease +1 Carle Physician Group Terminated No outcome recorded
NCT01347814 Feb 2008 → Apr 2010 diabetes mellitus University of Limerick Completed No outcome recorded
NCT00552422 Mar 2007 → Sep 2010 gastroesophageal reflux disease, gastroparesis David J. Lederer, M.D. Terminated No outcome recorded
Phase not stated7 trials
NCT02567175 constipation disorder, gastroesophageal reflux disease, gastroparesis, intestinal pseudo-obstruction Prasanna K Kapavarapu No longer available No outcome recorded
NCT04996134 gastroparesis Wake Forest University Health Sciences No longer available No outcome recorded
NCT03810287 gastroparesis Yale University No longer available No outcome recorded
NCT02494687 idiopathic gastroparesis Eastern Regional Medical Center Available No outcome recorded
NCT02227927 gastroesophageal reflux disease, gastroparesis Scott Gabbard, MD No longer available No outcome recorded
NCT03128398 gastroparesis Palo Alto Medical Foundation No longer available No outcome recorded
NCT02757534 gastroparesis Yehudith Assouline-Dayan No longer available No outcome recorded
Also used as a comparator or background therapy in 17 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT03221855 Comparator Mar 2013 → Dec 2015 Hospital de Clinicas de Porto Alegre Completed No outcome recorded
Phase 11 trial
Phase 1 NCT01021475 Comparator Nov 2009 → Nov 2010 dyspepsia International College of Osteopathic Medicine Unknown No outcome recorded
Phase 23 trials
Phase 2 NCT05596006 Comparator Dec 2022 → Mar 2023 Gadjah Mada University Completed No outcome recorded
Phase 2 NCT01512225 Comparator May 2012 → Oct 2015 Sunnybrook Health Sciences Centre Completed No outcome recorded
Phase 2 NCT00006077 Background Aug 2000 → Jul 2003 Parkinson disease National Institute of Neurological Disorders and Stroke (NINDS) Completed No outcome recorded
Phase 33 trials
Phase 3 NCT05570292 Comparator Oct 2022 → Apr 2023 Ain Shams University Completed No outcome recorded
Phase 3 NCT01257672 Comparator Jul 2011 → Nov 2013 gastroenteritis IRCCS Burlo Garofolo Completed No outcome recorded
Phase 3 NCT01355276 Comparator Oct 2010 → Jun 2011 dyspepsia Eisai Inc. Completed No outcome recorded
Phase 46 trials
Phase 4 NCT07578402 Comparator May → Dec 2026 expected dyspepsia Rakibul Mostafa Not yet recruiting No outcome recorded
Phase 4 NCT05030116 Comparator Jun 2019 → May 2020 dyspepsia Ruijin Hospital Completed No outcome recorded
Phase 4 NCT03806062 Comparator Jan → Dec 2018 lactation disease Cairo University Completed No outcome recorded
Phase 4 NCT02264587 Comparator Oct 2014 → Sep 2015 gastroparesis Liangzhou Wei Unknown No outcome recorded
Phase 4 NCT02140073 Comparator Dec 2013 → Jun 2014 gastroesophageal reflux disease Belarusian Medical Academy of Post-Graduate Education Unknown No outcome recorded
Phase not applicable3 trials
NCT04104867 Comparator Sep 2019 → Oct 2022 Mahidol University Unknown No outcome recorded
NCT00874133 Comparator Mar 2009 → Dec 2013 gastroparesis Rabin Medical Center Terminated No outcome recorded
NCT00604942 Background Nov 2007 → Oct 2010 achalasia, gastroesophageal reflux disease Guy's and St Thomas' NHS Foundation Trust Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 55 sources stand behind the page.

FieldValueCited text
Known as Domperidone “0.2mg group-The premature infant will be fed with 0.2mg/kg/tds domperidone and will be tested the residual glucose everyday in a 7-days period.” NCT02980250
53

Domperidone 1 tablet per os” NCT04802785

Domperidone capsule 10 mg” NCT05596006

NCT01021475

NCT00760461

NCT00308334

NCT02140073

NCT00305331

NCT03128398

NCT03806062

NCT02264587

NCT04104867

NCT03022201

NCT04699591

NCT01710462

NCT00238056

NCT01257672

NCT01643889

NCT02699385

NCT02958046

NCT01378884

NCT02816853

NCT00604942

NCT01780909

NCT07578402

NCT02308137

NCT02757534

NCT00761254

NCT02685436

NCT05570292

NCT02493049

NCT00284024

NCT01878526

NCT06695962

NCT00552422

NCT05030116

NCT00777439

NCT01711918

NCT04583111

NCT03810287

NCT00006077

NCT01355276

NCT01696734

NCT01347814

NCT03221855

NCT02227927

NCT04996134

NCT03617016

NCT02494687

NCT03662113

NCT02567175

NCT00103597

NCT03355170

NCT01512225

Known as Domperidone / Motilium Domperidone / MotiliumNCT01378884
Known as Domperidone Suspension(Motilium), B12200018238 Domperidone Suspension(Motilium), B12200018238NCT02980250
Known as motilium “compare Cinitapride tablets with domperidone tablets (motilium), and to evaluate the efficacy and safety of Cinitapride tablets in the treatment of mild to moderate functional...” NCT01355276
2

“2 tablets of Motilium® (API: domperidone 10 mg) 20 minutes before the intake of Gabbroral® oral tablet formulation” NCT01780909

NCT00874133

Action Inhibit “Domperidone, a drug that enhances upper gastric motility, is an anti-dopaminergic medication that also elevates prolactin levels.” NCT00308334
Route Oral “10 mg po TID X 14 days” NCT00308334