Drugs / Rabies vaccine
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Rabies vaccine

Vaccine

Developed for
rabies · malaria · viral infectious disease
Investigated by
GlaxoSmithKline · Walter Reed Army Institute of Research (WRAIR) · Chulalongkorn University · National Institute of Allergy and Infectious Diseases (NIAID) · Queen Saovabha Memorial Institute · State University of New York - Upstate Medical University
+23 more · U.S. Army Medical Research and Development Command · African Malaria Network Trust · Beijing Institute of Biological Products Co Ltd. · Changchun Institute of Biological Products Co., Ltd. · China National Biotec Group Company Limited · Guizhou Center for Disease Control and Prevention · Institute of Tropical Medicine, Belgium · International Centre for Diarrhoeal Disease Research, Bangladesh · Kamada, Ltd. · Kansas State University · Kenya Medical Research Institute · Lanzhou Institute of Biological Products Co., Ltd · Leiden University Medical Center · Novartis Vaccines · Peking University People's Hospital · Provincial Public Health Office, Phetchabun · Shaanxi Provincial Center for Disease Control and Prevention · Synermore Biologics Co., Ltd. · United States Agency for International Development (USAID) · University of Maryland, Baltimore · University of Oxford · Washington University School of Medicine · inVentiv Health Clinical

Trials 24 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT07399951 Oct 2023 → Jun 2025 Washington University School of Medicine Completed No outcome recorded
Phase 15 trials
Phase 1 NCT04715867 Jan 2021 → Dec 2022 International Centre for Diarrhoeal Disease Research, Bangladesh Unknown No outcome recorded
Phase 1 NCT04019444 Sep 2019 → Mar 2023 rabies National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1 NCT02458092 Apr → Dec 2008 malaria U.S. Army Medical Research and Development Command Completed No outcome recorded
Phase 1 NCT00424944 Jun 2007 → Jul 2008 malaria African Malaria Network Trust Unknown No outcome recorded
Phase 1 NCT00358332 Nov 2006 → Dec 2007 Plasmodium falciparum malaria U.S. Army Medical Research and Development Command Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02956746 Aug 2016 → Dec 2017 rabies Synermore Biologics Co., Ltd. Completed No outcome recorded
Phase 24 trials
Phase 2 NCT07445815 Jan → Jul 2026 overdue Lanzhou Institute of Biological Products Co., Ltd Not yet recruiting No outcome recorded
Phase 2 NCT06799234 Jul 2025 → Mar 2026 overdue Rift valley fever University of Oxford Active not recruiting No outcome recorded
Phase 2 NCT03276962 Sep 2017 → Nov 2019 malaria GlaxoSmithKline Completed No outcome recorded
Phase 2 NCT02276625 Oct 2014 → Feb 2016 rabies Leiden University Medical Center Unknown No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT02040090 Apr 2013 → Aug 2014 rabies Kamada, Ltd. Completed No outcome recorded
Phase 34 trials
Phase 3 NCT07455318 May 2026 → Jun 2027 expected Institute of Tropical Medicine, Belgium Not yet recruiting No outcome recorded
Phase 3 NCT02545517 Oct 2015 → Dec 2022 rabies GlaxoSmithKline Completed No outcome recorded
Phase 3 NCT01680016 Sep 2012 → Jan 2013 rabies Novartis Vaccines Completed No outcome recorded
Phase 3 NCT01107275 Nov 2002 → Nov 2004 rabies Provincial Public Health Office, Phetchabun Completed No outcome recorded
Phase 46 trials
Phase 4 NCT05453487 Jul → Oct 2022 COVID-19, rabies China National Biotec Group Company Limited Unknown No outcome recorded
Phase 4 NCT03192371 Feb 2018 → May 2019 viral infectious disease GlaxoSmithKline Withdrawn No outcome recorded
Phase 4 NCT02564471 Nov 2016 → Aug 2018 rabies State University of New York - Upstate Medical University Completed No outcome recorded
Phase 4 NCT02490956 Apr 2015 → Sep 2016 immunodeficiency disease Chulalongkorn University Unknown No outcome recorded
Phase 4 NCT02374814 Mar 2015 → Sep 2016 rabies State University of New York - Upstate Medical University Completed No outcome recorded
Phase 4 NCT01173302 May → Aug 2010 rabies Peking University People's Hospital Unknown No outcome recorded
Phase not applicable2 trials
NCT02547727 Feb 2016 → Dec 2023 rabies Queen Saovabha Memorial Institute Unknown No outcome recorded
NCT01641315 Sep 2015 → Apr 2018 rabies Queen Saovabha Memorial Institute Completed No outcome recorded
Also used as a comparator or background therapy in 50 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 111 trials
Phase 1 NCT07124156 Comparator Mar → Jul 2026 overdue malaria European Vaccine Initiative Not yet recruiting No outcome recorded
Phase 1 NCT07342257 Background Nov 2024 → May 2025 rabies Synermore Biologics (Suzhou) Co., Ltd. Completed No outcome recorded
Phase 1 NCT06048770 Comparator Sep 2023 → Jul 2024 Replicate Bioscience Terminated No outcome recorded
Phase 1 NCT05644067 Comparator Aug 2023 → Apr 2024 malaria Swiss Tropical & Public Health Institute Completed No outcome recorded
Phase 1 NCT05135273 Comparator Oct 2021 → Feb 2023 Plasmodium falciparum malaria National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1/22 trials
Phase 1/2 NCT04495569 Background Feb → Jun 2019 rabies Synermore Biologics (Suzhou) Co., Ltd. Completed No outcome recorded
Phase 1/2 NCT01635647 Comparator Nov 2012 → Aug 2014 malaria University of Oxford Completed No outcome recorded
Phase 216 trials
Phase 2 NCT07055880 Comparator Jul 2025 → Jan 2026 overdue rabies Sinovac Biotech Co., Ltd Not yet recruiting No outcome recorded
Phase 2 NCT03961555 Background Sep 2019 → Dec 2021 rabies Synermore Biologics Co., Ltd. Completed No outcome recorded
Phase 2 NCT02956421 Comparator Feb → Oct 2016 rabies Yisheng Biopharma (Singapore) Pte. Ltd. Completed No outcome recorded
Phase 2 NCT01658696 Comparator Aug 2012 → Feb 2013 malaria University of Oxford Completed No outcome recorded
Phase 2 NCT01666925 Comparator Mar → Aug 2012 malaria University of Oxford Completed No outcome recorded
Phase 2/32 trials
Phase 2/3 NCT07345208 Comparator Dec 2025 → May 2027 expected rabies International Centre for Diarrhoeal Disease Research, Bangladesh Not yet recruiting No outcome recorded
Phase 2/3 NCT03264157 Background Dec 2017 → Mar 2018 Bio Products Laboratory Completed No outcome recorded
Phase 316 trials
Phase 3 NCT07055295 Comparator Mar → Dec 2026 expected rabies Sinovac Biotech Co., Ltd Not yet recruiting No outcome recorded
Phase 3 NCT07055893 Comparator Mar 2026 → Jan 2027 expected Sinovac Biotech Co., Ltd Not yet recruiting No outcome recorded
Phase 3 NCT05846568 Background Oct 2022 → Sep 2023 rabies Genrix (Shanghai) Biopharmaceutical Co., Ltd. Completed No outcome recorded
Phase 3 NCT04704830 Background Apr 2021 → Mar 2023 overdue Plasmodium falciparum malaria University of Oxford Active not recruiting No outcome recorded
Phase 3 NCT04594551 Comparator Oct 2020 → Jun 2021 Sanofi Pasteur, a Sanofi Company Completed No outcome recorded
Phase 43 trials
Phase 4 NCT03557008 Comparator Jul 2018 → Jun 2022 rabies Emory University Completed No outcome recorded
Phase 4 NCT01365494 Comparator Jul → Nov 2011 rabies Novartis Vaccines Completed No outcome recorded
Phase 4 NCT00023504 Comparator Jun 2002 → May 2017 immunodeficiency disease National Institute of Allergy and Infectious Diseases (NIAID) Terminated No outcome recorded

Evidence & citations 16 cited values

Every value below carries the sentence it was read from. 78 sources stand behind the page.

FieldValueCited text
Known as Rabies vaccine Rabies vaccine (RabAvert): RabAvert Rabies vaccine” NCT00349713
30

“purified chick-embryo cell-culture rabies vaccineNCT07455318

NCT03276962

NCT00460525

NCT02177032

NCT07342257

NCT07445815

NCT01658696

NCT07345208

NCT06799234

NCT01641315

NCT04495569

NCT02547727

NCT01466387

NCT03557008

NCT02276625

NCT00031070

NCT02564471

NCT00703066

NCT00345319

NCT04644484

NCT05846568

NCT02374814

NCT01173302

NCT03961555

NCT07055893

NCT00703521

NCT01635647

NCT01666925

NCT05453487

NCT04704830

Known as Abhayrab “licensed rabies vaccine [Abhayrab]” PMID 38310910 Feb 2024
Known as Cell-culture rabies vaccine ClinicalTrials.gov intervention name — accepted as the source's own label NCT02207816
1

NCT00866619

Known as ChengDa rabies vaccine “Our findings demonstrate that the ChengDa rabies vaccine offers an alternative with a high degree of efficacy and yet limited side effects and ensures that the exposed patient...” PMID 21752947 Jul 2011
Known as Inactivated rabies virus vaccine ClinicalTrials.gov intervention name — accepted as the source's own label NCT00842530
Known as PCEC rabies vaccine “12 doses of the PCEC rabies vaccine, administered ID (0.1mL for each injection)” NCT02177032
Known as PCECV, Rabipur PCECV, RabipurNCT01107275
Known as Purified inactivated rabies vaccine ClinicalTrials.gov intervention name — accepted as the source's own label NCT04478084
Known as PVRV “licensed purified Vero cell vaccine (PVRV; Verorab)” PMID 38478634 Jun 2024
1

“Verorab® (PVRV; Purified Vero Cell Vaccine)” NCT02490956

Known as RabAvert “The RABAVERT Vaccine is an inactivated, purified chick embryo cell vaccine (PCECV). It consists of lyophilized rabies virus (strain Flury LEP) that has been propagated in...” NCT04019444
11

“We conducted a first-in-human, phase 1, randomized, double-blind, dose-escalation trial comparing ChAd155-RG with a licensed inactivated vaccine (RabAvert) in healthy adults.” PMID 39418686 Oct 2024

RabAvert®” NCT02040090

NCT00223990

NCT04062669

NCT02956746

NCT06048770

NCT07399951

NCT00349713

NCT00023504

NCT03264157

NCT00358332

Known as Rabipur “Male or female subjects between 5 and 17 months of age at the time of first vaccination received 3 doses of Rabipur vaccine administered intramuscularly in the left deltoid...” NCT00380393
13

“2 or 3 intradermal doses of 0.1 mL PCECV (Rabipur) were administered to 703 schoolchildren on days 0 and 28 or on days 0, 7, and 28.” PMID 17643772 Aug 2007

“Two group (Zagreb and Essen) will receive Rabipur vaccine IM according to either Zagreb or Essen schedules.” NCT01365494

“Subjects received Zagreb schedule (2-1-1) i.e. 4 vaccinations of Rabipur at days 1 , 8 and 22” NCT01680016

NCT03713086

NCT02545517

NCT02238756

NCT02956421

NCT00197054

NCT02458092

NCT03192371

NCT02657161

NCT03143218

NCT00360230

Known as Rabix-VC ClinicalTrials.gov intervention name — accepted as the source's own label NCT04715867
Known as RVa “Imovax (RVi) and Rabavert (RVa) rabies vaccines” NCT02956746
Known as Verorab “A next-generation, serum-free, highly purified Vero cell rabies vaccine is safe and as immunogenic as the reference vaccine Verorab® when administered according to a...” PMID 24148575 Oct 2013
14

Verorab was licensed in 1985 for both pre- and post-exposure prophylaxis of rabies.” PMID 23510665 Mar 2013

“licensed purified Vero cell vaccine (PVRV; Verorab)” PMID 38478634 Jun 2024

“Group 2: Verorab + HRIG” NCT04594551

NCT00424944

NCT05135273

NCT02490956

NCT01341704

NCT07055893

NCT07055880

NCT07055295

NCT07124156

NCT00652275

NCT04127786

NCT05644067

Modality Vaccine “using Rabies vaccine immunization” NCT00023504
Route Intramuscular “administered intramuscular deltoid” NCT00197054