Drugs / Enlonstobart

Trials 25 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03852823 May 2019 → Sep 2022 cervical cancer, lymphoma, malignant mesothelioma, non-small cell lung carcinoma CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Unknown No outcome recorded
Phase 1/26 trials
Phase 1/2 NCT07622225 May 2026 → Dec 2028 expected neoplasm CSPC Megalith Biopharmaceutical Co.,Ltd. Not yet recruiting No outcome recorded
Phase 1/2 NCT07282509 Dec 2025 → Jun 2028 expected hepatocellular carcinoma CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Not yet recruiting No outcome recorded
Phase 1/2 NCT07288814 Dec 2025 → Dec 2026 expected peripheral T-cell lymphoma, not otherwise specified Sun Yat-sen University Cancer Center Not yet recruiting No outcome recorded
Phase 1/2 NCT06132217 Jan 2024 → Jan 2027 expected neoplasm Shanghai Runshi Pharmaceutical Technology Co., Ltd Not yet recruiting No outcome recorded
Phase 1/2 NCT06136988 Dec 2023 → Apr 2027 expected esophageal squamous cell carcinoma CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Not yet recruiting No outcome recorded
Phase 1/2 NCT05508659 Sep 2022 → Sep 2024 cancer CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Unknown No outcome recorded
Phase 211 trials
Phase 2 NCT07448077 Mar 2026 overdue Hebei Medical University Fourth Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07281157 Nov 2025 → Apr 2027 expected rectal cancer Tianjin Medical University Cancer Institute and Hospital Recruiting No outcome recorded
Phase 2 NCT06989671 Aug 2025 → Dec 2027 expected head and neck squamous cell carcinoma CSPC Megalith Biopharmaceutical Co.,Ltd. Not yet recruiting No outcome recorded
Phase 2 NCT06998771 Jun 2025 → Jun 2028 expected carcinoma Shanghai JMT-Bio Inc. Not yet recruiting No outcome recorded
Phase 2 NCT06981858 May 2025 → Feb 2029 expected cervical carcinoma Chongqing University Cancer Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07183865 Mar 2025 → Mar 2030 expected rectal cancer Fudan University Recruiting No outcome recorded
Phase 2 NCT06089330 Jan → Jul 2024 colorectal cancer Shanghai JMT-Bio Inc. Unknown No outcome recorded
Phase 2 NCT05068141 Oct 2021 → Oct 2022 triple-negative breast carcinoma CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Unknown No outcome recorded
Phase 2 NCT05009953 Sep 2021 → Jan 2023 gallbladder carcinoma, intrahepatic cholangiocarcinoma CSPC Ouyi Pharmaceutical Co., Ltd. Terminated No outcome recorded
Phase 2 NCT04983550 Sep 2021 → Jan 2023 fallopian tube cancer, malignant epithelial tumor of ovary, peritoneum cancer CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Unknown No outcome recorded
Phase 2/34 trials
Phase 2/3 NCT07662811 Jun 2026 → Dec 2027 expected non-small cell lung carcinoma Shanghai Chest Hospital Not yet recruiting No outcome recorded
Phase 2/3 NCT07585279 May 2026 → Feb 2031 expected colorectal cancer Hebei Medical University Fourth Hospital Not yet recruiting No outcome recorded
Phase 2/3 NCT07332533 Dec 2025 → Jun 2032 expected carcinoma Shanghai JMT-Bio Inc. Not yet recruiting No outcome recorded
Phase 2/3 NCT07251062 Dec 2025 → Dec 2029 expected esophageal squamous cell carcinoma CSPC Megalith Biopharmaceutical Co.,Ltd. Not yet recruiting No outcome recorded
Phase 33 trials
Phase 3 NCT07672223 Jun 2026 → Sep 2029 expected non-small cell lung carcinoma CSPC Megalith Biopharmaceutical Co.,Ltd. Not yet recruiting No outcome recorded
Phase 3 NCT07633873 Jun 2026 → Sep 2027 expected non-small cell lung carcinoma CSPC Megalith Biopharmaceutical Co.,Ltd. Not yet recruiting No outcome recorded
Phase 3 NCT05715840 Jan 2023 → Jul 2024 CSPC ZhongQi Pharmaceutical Technology Co., Ltd. Unknown No outcome recorded
Also used as a comparator or background therapy in 3 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT06682611 Comparator Nov 2024 → Nov 2026 expected Shanghai Runshi Pharmaceutical Technology Co., Ltd Not yet recruiting No outcome recorded
Phase 22 trials
Phase 2 NCT07714668 Comparator Aug 2026 → Apr 2028 expected ovarian cancer CSPC Megalith Biopharmaceutical Co.,Ltd. Not yet recruiting No outcome recorded
Phase 2 NCT07254585 Background Dec 2025 → Jun 2026 overdue head and neck squamous cell carcinoma CSPC Megalith Biopharmaceutical Co.,Ltd. Recruiting No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 29 sources stand behind the page.

FieldValueCited text
Known as Enlonstobart Enlonstobart (SG001) is a fully humanized and high-affinity anti-PD-1 immunoglobulin G4 monoclonal antibody.” PMID 39447517 Oct 2024
14

Enlonstobart Enlonstobart 200mg IV every 3 weeks” NCT07448077

Enlonstobart: 240mg, ivgtt, d1” NCT07281157

NCT07254585

NCT07714668

NCT07622225

NCT07332533

NCT07672223

NCT06981858

NCT07662811

NCT07585279

NCT06998771

NCT07288814

NCT07633873

NCT07282509

Known as SG001 “Enlonstobart (SG001) is a fully humanized and high-affinity anti-PD-1 immunoglobulin G4 monoclonal antibody.” PMID 39447517 Oct 2024
13

NCT06989671

NCT06132217

NCT03852823

NCT06682611

NCT06089330

NCT05508659

NCT05715840

NCT05009953

NCT06136988

NCT04983550

NCT07183865

NCT07251062

NCT05068141

Known as SG001: Enlonstobart SG001: EnlonstobartNCT07251062
Action Inhibit “novel PD-1 inhibitor” PMID 39447517 Oct 2024
Modality Monoclonal antibody “SG001 is a humanized, IgG4 monoclonal antibody against human PD-1.” PMID 41321671 Nov 2025
Route Intravenous “Subjects will receive intravenous infusion of SG001” NCT03852823
Target PDCD1 “SG001 is a humanized, IgG4 monoclonal antibody against human PD-1.” PMID 41321671 Nov 2025