drugset / Trial / NCT06989671

SYS6002 Plus JMT101 and Enlonstobart Injection in Participants With HNSCC

NCT06989671

Phase 2 Not yet recruiting 430 enrolled CSPC Megalith Biopharmaceutical Co.,Ltd.
RandomizedFactorialOpen-labelTreatment

Summary

This is a Phase II study of anti-nectin-4 ADC combined with the EGFR monoclonal antibody and the PD-1 monoclonal antibody in participants with advanced head and neck squamous cell carcinoma.

Timeline

Start
2025-08-30
Primary completion
2027-12-30
Completion
2028-07-30

Drugs

EvaluationDrugModalityDoseRoute
Subject BECOTATUG Monoclonal antibody Intravenous
Subject Enlonstobart Monoclonal antibody Intravenous
Subject SYS6002 Other / unclassified Intravenous