Drugs / OPIGOLIX
last change May 2019 re-read 2 minutes ago

OPIGOLIX

also known as ASP1707 · Opigolixum

Other / unclassified targets GNRHR via inhibition

Developed for
rheumatoid arthritis · endometriosis
Investigated by
Astellas Pharma Europe B.V. · Astellas Pharma Global Development, Inc. · Astellas Pharma Inc

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT02867306 Jul → Aug 2016 rheumatoid arthritis Astellas Pharma Global Development, Inc. Completed No outcome recorded
Phase 1 NCT02175407 Apr → Jun 2014 Astellas Pharma Europe B.V. Completed No outcome recorded
Phase 1 NCT02106780 Aug → Sep 2011 Astellas Pharma Europe B.V. Completed No outcome recorded
Phase 1 NCT02146742 Jun → Aug 2011 Astellas Pharma Europe B.V. Completed No outcome recorded
Phase 1 NCT02368912 Jun 2010 → Aug 2011 Astellas Pharma Europe B.V. Completed No outcome recorded
Phase 22 trials
Phase 2 NCT02884635 Sep 2016 → Oct 2017 rheumatoid arthritis Astellas Pharma Inc Completed No outcome recorded
Phase 2 NCT01767090 Dec 2012 → May 2015 endometriosis Astellas Pharma Europe B.V. Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as OPIGOLIX ChEMBL registry synonym — accepted as the source's own label CHEMBL3989969
Known as ASP1707 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02884635
6

NCT02146742

NCT02175407

NCT01767090

NCT02368912

NCT02867306

NCT02106780

Known as Opigolixum ChEMBL registry synonym — accepted as the source's own label CHEMBL3989969
Action Inhibit “Gonadotropin-releasing hormone receptor antagonist” CHEMBL3989969
1

“GnRH antagonist, ASP1707” PMID 31067329 May 2019

Modality Other / unclassified “GnRH antagonist, ASP1707” PMID 31067329 May 2019
Route Oral OralNCT01767090
Target GNRHR “Gonadotropin-releasing hormone receptor antagonist” CHEMBL3989969