Drugs / OPIGOLIX
last change May 2019 re-read 9 days ago

OPIGOLIX

also known as ASP1707 · Opigolixum

Other / unclassified targets GNRHR via inhibition

Developed for
rheumatoid arthritis · endometriosis
Investigated by
Astellas Pharma Europe B.V. · Astellas Pharma Global Development, Inc. · Astellas Pharma Inc

Trials 7

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT02867306 Jul → Aug 2016 rheumatoid arthritis Astellas Pharma Global Development, Inc. Completed No outcome recorded
Phase 1 NCT02175407 Apr → Jun 2014 — Astellas Pharma Europe B.V. Completed No outcome recorded
Phase 1 NCT02106780 Aug → Sep 2011 — Astellas Pharma Europe B.V. Completed No outcome recorded
Phase 1 NCT02146742 Jun → Aug 2011 — Astellas Pharma Europe B.V. Completed No outcome recorded
Phase 1 NCT02368912 Jun 2010 → Aug 2011 — Astellas Pharma Europe B.V. Completed No outcome recorded
Phase 22 trials · 1 met primary
Phase 2 NCT02884635 Sep 2016 → Oct 2017 rheumatoid arthritis Astellas Pharma Inc Completed No outcome recorded
Phase 2 NCT01767090 Dec 2012 → May 2015 endometriosis Astellas Pharma Europe B.V. Completed Met primary

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 9 sources stand behind the page.

FieldValueCited text
Known as OPIGOLIX ChEMBL registry synonym — accepted as the source's own label CHEMBL3989969 ↗
Known as ASP1707 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02106780 ↗
6

NCT02175407 ↗

NCT02368912 ↗

NCT02867306 ↗

NCT02146742 ↗

NCT02884635 ↗

NCT01767090 ↗

Known as Opigolixum ChEMBL registry synonym — accepted as the source's own label CHEMBL3989969 ↗
Action Inhibit “Gonadotropin-releasing hormone receptor antagonist” CHEMBL3989969 ↗
1

“GnRH antagonist, ASP1707” PMID 31067329 ↗ May 2019

Modality Other / unclassified “GnRH antagonist, ASP1707” PMID 31067329 ↗ May 2019
Route Oral “Oral” NCT01767090 ↗
Target GNRHR “Gonadotropin-releasing hormone receptor antagonist” CHEMBL3989969 ↗