drugset / Trial / NCT02867306

A Study to Evaluate the Pharmacokinetics of ASP1707 and Methotrexate in Patients With Rheumatoid Arthritis

NCT02867306

Phase 1 Completed 10 enrolled Astellas Pharma Global Development, Inc.
NaSingle-groupOpen-labelTreatment

Summary

The primary purpose of the study is to evaluate the effect of ASP1707 twice daily on the pharmacokinetics of once weekly oral methotrexate (MTX). This study will also evaluate the effect of MTX on multiple-dose pharmacokinetics of ASP1707, as well as safety and tolerability of coadministration of ASP1707 and MTX in patients with rheumatoid arthritis (RA).

Timeline

Start
2016-07-25
Primary completion
2016-08-30
Completion
2016-08-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Methotrexate Small molecule Oral
Subject OPIGOLIX Other / unclassified Oral

Indications