Drugs / Keratinocyte Growth Factor
last change Mar 2026 re-read 3 minutes ago

Keratinocyte Growth Factor

also known as KGF · KGF-hair serum · KGF-HS · rHuKGF

Protein / enzyme biologic

Developed for
acute graft versus host disease · chemotherapy-induced alopecia · asthma
Investigated by
FDA Office of Orphan Products Development · University of Arizona

Trials 2

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial · 1 missed
Phase 0 NCT04554732 Apr 2020 → Jun 2022 chemotherapy-induced alopecia University of Arizona Completed Missed primary
Phase 1/21 trial
Phase 1/2 NCT00031148 Sep 2001 → Aug 2003 acute graft versus host disease FDA Office of Orphan Products Development Completed No outcome recorded
Comparator or background therapy2 trials
Phase 0 NCT02653196 Background Sep 2015 → Aug 2017 neuroepithelial neoplasm Montefiore Medical Center Terminated No outcome recorded
Phase 2 NCT01386151 Comparator Aug 2009 → Jul 2011 asthma University Hospital Southampton NHS Foundation Trust Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as Keratinocyte Growth Factor ClinicalTrials.gov intervention name — accepted as the source's own label NCT02653196 ↗
3

NCT00031148 ↗

NCT04554732 ↗

NCT01386151 ↗

Known as KGF “Keratinocyte growth factor (KGF) has been shown to have cytoprotective effects on human hair follicles and reduce alopecia in preclinical models.” PMID 41834767 ↗ Mar 2026
Known as KGF-hair serum “We hypothesized that KGF-hair serum (KGF-HS) will prevent CIA.” PMID 41834767 ↗ Mar 2026
Known as KGF-HS “We hypothesized that KGF-hair serum (KGF-HS) will prevent CIA.” PMID 41834767 ↗ Mar 2026
Known as rHuKGF “Keratinocyte Growth Factor (rHuKGF)” NCT00031148 ↗
Modality Protein / enzyme biologic “KGF is a protein that stimulates the growth of epithelial cells including those of the GI tract.” NCT00031148 ↗
Route Intravenous “KGF will be administered intravenously in a 'collapsed dose' regime of 180ug/kg on day 0 and day 11” NCT01386151 ↗