Keratinocyte Growth Factor- Hair Serum for the Prevention of Chemotherapy Induced Alopecia

Summary

Primary aim is to provide a preliminary assessment of the efficacy of the investigational topical formula, KGF-HS, as a prophylactic treatment for chemotherapy induced alopecia. Hypothesis: KGF-HS will result in less than 50% hair loss by the end of 4 cycles of chemotherapy. The investigators will evaluate hair loss using the CTCAE (Common Terminology Criteria for Adverse Events) v4.0 alopecia grading scale.

Timeline

Start

2020-04-27

Primary completion

2022-06-24

Completion

2022-06-24

Publications

• Mann K, Potluri P, Paul EE, Segar JM, Ehsani S, Roe D, Chalasani P. A Nonrandomized Clinical Trial Investigating Keratinocyte Growth Factor-Hair Serum for the Prevention of Chemotherapy-Induced Alopecia. J Cosmet Dermatol. 2026 Mar;25(3):e70797. doi: 10.1111/jocd.70797.

Drugs

Indications