Drugs / Secretome
Secretome
Trials 11
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 15 trials | ||||||
| Phase 1 | NCT06638970 | Dec 2024 → Oct 2025 overdue | epilepsy | Baermed | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06629909 | Dec 2024 → Oct 2025 overdue | cirrhosis of liver | Baermed | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06632470 | Oct 2024 → May 2025 overdue | dementia | Baermed | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06217627 | Mar 2021 → Jan 2023 | — | COR clinic of Regenerative Medicine | Completed | No outcome recorded |
| Phase 1 | NCT05777213 | Jan 2019 → Jan 2022 | chronic ulcer of skin, leprosy | Yohanes Firmansyah, dr, MH, MM | Completed | No outcome recorded |
| Phase 1/24 trials | ||||||
| Phase 1/2 | NCT07429253 | Jan → Jun 2026 overdue | androgenetic alopecia | PT. Prodia Stem Cell Indonesia | Recruiting | No outcome recorded |
| Phase 1/2 | NCT07439848 | Dec 2023 → Dec 2026 expected | acute respiratory distress syndrome | PT. Prodia Stem Cell Indonesia | Recruiting | No outcome recorded |
| Phase 1/2 | NCT05921058 | Aug → Dec 2022 | lupus erythematosus | Universitas Sebelas Maret | Completed | No outcome recorded |
| Phase 1/2 | NCT04314661 | Aug 2020 → Jul 2024 | osteoarthritis, knee | PT. Prodia Stem Cell Indonesia | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT06925386 | May → Dec 2025 overdue | acne | Padjadjaran University | Not yet recruiting | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT06469411 | Jan → Jun 2023 | graft versus host disease | Tabriz University of Medical Sciences | Completed | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| — | NCT07137130 Background | Feb → May 2026 overdue | hyperpigmentation of the skin | Indonesia University | Not yet recruiting | No outcome recorded |
News releases announcing trial results or a regulatory action · 3
| Date | Issuer | Release |
|---|---|---|
| 2024-12-17 | Aposcience AG | Results Paper on content analysis of APOSEC recently published aposcience.at ↗
We found that the potency for preventing ventricular remodeling was similar with the GMP-compliant and experimentally-prepared PBMC secretomes. |
| 2015-03-31 | Aposcience AG | Results APOSEC attenuates secondary damage following spinal cord injury aposcience.at ↗
The secretome of apoptotic human peripheral blood mononuclear cells attenuates secondary damage following spinal cord injury in rats |
| 2014-01-30 | Aposcience AG | Results Effect of APOSEC on chronic ischemic left ventricular dysfunction aposcience.at ↗
In conclusion, over- expression of MEF2c and repression of caspase was related to decreased infarct size and improved cardiac function in secretome-treated animals. |
All press releases naming this drug 3 releases
| Date | Issuer | Release |
|---|---|---|
| 2024-12-17 | Aposcience AG | Paper on content analysis of APOSEC recently published aposcience.at ↗ |
| 2015-03-31 | Aposcience AG | APOSEC attenuates secondary damage following spinal cord injury aposcience.at ↗ |
| 2014-01-30 | Aposcience AG | Effect of APOSEC on chronic ischemic left ventricular dysfunction aposcience.at ↗ |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 12 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | secretome | ClinicalTrials.gov intervention name — accepted as the source's own label NCT07137130 ↗ |
| Known as | ADMSCS | “Development Of Adipose-Derived Mesenchymal Stem Cells Secretome (ADMSCS) Based Products From Stem Cell Conditioned Medium For Melasma Therapy” NCT07137130 ↗ |
| Known as | CM-WJMSCs | “The interventions given in this study were Conditioned Medium Wharton's Jelly-derived mesenchymal stem cells (CM-WJMSCs) as much as 0.1cc / 1cm intracutaneously with a flexpen...” NCT05777213 ↗ |
| Modality | Other / unclassified | “Conditioned Medium Wharton's Jelly-derived mesenchymal stem cells (CM-WJMSCs)” NCT05777213 ↗ |
| Route | Other | “via Intra-articular” NCT04314661 ↗ |