Drugs / CD4 CAR+CCR5 ZFN T-cells
last change Jul 2019 re-read 3 minutes ago

CD4 CAR+CCR5 ZFN T-cells

Cell therapy targets CCR5 via inhibition

Developed for
HIV infectious disease
Investigated by
University of Pennsylvania

Trials 1

20202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03617198 Jul 2019 → Dec 2026 expected HIV infectious disease University of Pennsylvania Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as CD4 CAR+CCR5 ZFN T-cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT03617198 ↗
Action Inhibit “zinc finger nuclease-mediated disruption of the CCR5 gene” NCT03617198 ↗
Modality Cell therapy “single infusion of autologous T cells genetically modified to express a CD4 chimeric antigen receptor” NCT03617198 ↗
Target CCR5 “zinc finger nuclease-mediated disruption of the CCR5 gene” NCT03617198 ↗