drugset / Trial / NCT03617198

CD4 CAR+ ZFN-modified T Cells in HIV Therapy

NCT03617198 ↗

Phase 1 Active not recruiting 12 enrolled University of Pennsylvania
RandomizedParallel-groupOpen-labelTreatment

Summary

This research study is being carried out to study a new way to possibly treat HIV. As part of this study, doctors will take some of your own white blood cells, called T-cells, and modify them so that they can identify and target your HIV cells. The purpose of the study is to evaluate the safety of these modified T cells and determine whether they have any effect on HIV infection.

Timeline

Start
2019-07-31
Primary completion
2026-12
Completion
2027-12

Drugs

EvaluationDrugModalityDoseRoute
Subject CD4 CAR+CCR5 ZFN T-cells Cell therapy 1e+10 cells —