Drugs / AKB-9778
last change Nov 2020 re-read 2 minutes ago

AKB-9778

also known as Razuprotafib
Developed for
diabetic macular edema · ocular hypertension · open-angle glaucoma · diabetic retinopathy · retinal vein occlusion
Investigated by
Aerpio Therapeutics · EyePoint Pharmaceuticals, Inc.

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT04284514 May → Dec 2019 ocular hypertension, open-angle glaucoma Aerpio Therapeutics Completed No outcome recorded
Phase 1 NCT02858271 Jul 2016 Aerpio Therapeutics Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT01702441 Sep 2012 → Sep 2013 diabetic macular edema Aerpio Therapeutics Completed No outcome recorded
Phase 24 trials
Phase 2 NCT04405245 Jun → Nov 2020 ocular hypertension, open-angle glaucoma EyePoint Pharmaceuticals, Inc. Completed No outcome recorded
Phase 2 NCT03197870 Jun 2017 → Jan 2019 diabetic retinopathy EyePoint Pharmaceuticals, Inc. Completed No outcome recorded
Phase 2 NCT02387788 Jan 2015 → Apr 2017 retinal vein occlusion Aerpio Therapeutics Completed No outcome recorded
Phase 2 NCT02050828 Jan 2014 → Apr 2015 diabetic macular edema Aerpio Therapeutics Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as AKB-9778 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02858271
6

NCT02050828

NCT03197870

NCT01702441

NCT04284514

NCT02387788

NCT04405245

Known as Razuprotafib “AKB-9778 (Razuprotafib), a Novel Tie 2 Activator” NCT03197870
Action Activate “AKB-9778, a Novel Tie-2 Activator” NCT02050828
Route Subcutaneous “given as subcutaneous injections” NCT01702441