drugset / Trial / NCT02050828

The TIME-2 Study: A Phase 2 Study of AKB-9778, a Novel Tie-2 Activator, in Patients With Diabetic Macular Edema

NCT02050828

Phase 2 Completed 144 enrolled Aerpio Therapeutics
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to evaluate the safety and efficacy of AKB-9778 administered as daily subcutaneous injections with and without monthly intravitreal injections of ranibizumab for 3 months in patients with diabetic macular edema.

Timeline

Start
2014-01
Primary completion
2015-04
Completion
2015-05

Drugs

EvaluationDrugModalityDoseRoute
Subject AKB-9778 Unknown 15 mg Subcutaneous
Subject Ranibizumab Monoclonal antibody 0.3 mg Intravitreal