Drugs / Na-GST-1
Na-GST-1
Trials 8 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 17 trials | ||||||
| Phase 1 | NCT03373214 | Feb 2018 → Feb 2019 | hookworm infectious disease | Baylor College of Medicine | Completed | No outcome recorded |
| Phase 1 | NCT02839161 | Jan 2017 → Dec 2018 | hookworm infectious disease | Baylor College of Medicine | Completed | No outcome recorded |
| Phase 1 | NCT02476773 | Jan 2016 → Jun 2017 | hookworm infectious disease | Baylor College of Medicine | Completed | No outcome recorded |
| Phase 1 | NCT02126462 | Nov 2014 → Feb 2016 | hookworm infectious disease | Baylor College of Medicine | Completed | No outcome recorded |
| Phase 1 | NCT02143518 | Oct 2014 → Jun 2016 | hookworm infectious disease | Baylor College of Medicine | Completed | No outcome recorded |
| Phase 1 | NCT01385189 | May 2012 → Jan 2015 | hookworm infectious disease | Baylor College of Medicine | Completed | No outcome recorded |
| Phase 1 | NCT01261130 | Nov 2011 → Aug 2014 | hookworm infectious disease | Baylor College of Medicine | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT03172975 | Mar 2018 → Dec 2024 | hookworm infectious disease | Baylor College of Medicine | Completed | No outcome recorded |
Evidence & citations 5 cited values
Every value below carries the sentence it was read from. 10 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Na-GST-1 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01385189 ↗ |
| Known as | N americanus glutathione S-transferase-1 | “Necator americanus aspartic protease-1 (Na-APR-1) and N americanus glutathione S-transferase-1 (Na-GST-1) are involved in the digestion and detoxification of haemoglobin in the...” PMID 32926834 ↗ Sep 2020 |
| Known as | Necator americanus Glutathione-S-Transferase-1 | “Necator americanus Glutathione-S-Transferase-1 (Na-GST-1) plays a role in the digestion of host hemoglobin by adult N. americanus hookworms.” PMID 28464026 ↗ May 2017 |
| Modality | Protein / enzyme biologic | “The Na-GST-1 vaccine formulations to be tested in this study consist of the 24 kDa recombinant protein Na-GST-1 adsorbed to Alhydrogel® either with or without the addition of GLA-AF.” NCT01261130 ↗ |
| Route | Intramuscular | “Vaccinations were administered via intramuscular injection on days 0, 56, and 112.” PMID 28464026 ↗ May 2017 |