Drugs / Apadenoson
last change Apr 2012 re-read 2 minutes ago

Apadenoson

also known as BMS-068645 · DWH-146E · Stedivaze

Small molecule targets ADORA2A via activation

Investigated by
Forest Laboratories · PPD Development, LP

Trials 5 · a red edge is where a trial was stopped

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT00162071 Jul 2005 → Mar 2006 myocardial ischemia Forest Laboratories Terminated No outcome recorded
Phase 34 trials
Phase 3 NCT01313572 Aug 2011 → Apr 2012 coronary artery disorder Forest Laboratories Terminated No outcome recorded
Phase 3 NCT00990327 Nov 2009 → Apr 2012 coronary artery disorder Forest Laboratories Terminated No outcome recorded
Phase 3 NCT00380198 Jul → Nov 2006 coronary artery disorder Forest Laboratories Terminated No outcome recorded
Phase 3 NCT00162084 Apr 2005 → Mar 2006 myocardial ischemia Forest Laboratories Terminated No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Apadenoson ClinicalTrials.gov intervention name — accepted as the source's own label NCT00380198
4

NCT00162071

NCT01313572

NCT00162084

NCT00990327

Known as BMS-068645 ChEMBL registry synonym — accepted as the source's own label CHEMBL1950649
Known as DWH-146E ChEMBL registry synonym — accepted as the source's own label CHEMBL1950649
Known as Stedivaze ChEMBL registry synonym — accepted as the source's own label CHEMBL1950649
Action Activate “Adenosine A2a receptor agonist” CHEMBL1950649
Modality Small molecule CHEMBL1950649
Route Intravenous “Apadenoson single bolus IV injection 100 or 150 ug” NCT00990327
Target ADORA2A “Adenosine A2a receptor agonist” CHEMBL1950649