Drugs / Apadenoson
last change Apr 2012 re-read 9 days ago

Apadenoson

also known as BMS-068645 · DWH-146E · Stedivaze

Small molecule targets ADORA2A via activation

Investigated by
Forest Laboratories · PPD Development, LP

Trials 5

20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT00162071 Jul 2005 → Mar 2006 myocardial ischemia Forest Laboratories Terminated No outcome recorded
Phase 34 trials
Phase 3 NCT01313572 Aug 2011 → Apr 2012 coronary artery disorder Forest Laboratories Terminated No outcome recorded
Phase 3 NCT00990327 Nov 2009 → Apr 2012 coronary artery disorder Forest Laboratories Terminated No outcome recorded
Phase 3 NCT00380198 Jul → Nov 2006 coronary artery disorder Forest Laboratories Terminated No outcome recorded Stop: Business
Phase 3 NCT00162084 Apr 2005 → Mar 2006 myocardial ischemia Forest Laboratories Terminated No outcome recorded Stop: Business

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as apadenoson ClinicalTrials.gov intervention name — accepted as the source's own label NCT00162071 ↗
4

NCT00380198 ↗

NCT00162084 ↗

NCT00990327 ↗

NCT01313572 ↗

Known as BMS-068645 ChEMBL registry synonym — accepted as the source's own label CHEMBL1950649 ↗
Known as DWH-146E ChEMBL registry synonym — accepted as the source's own label CHEMBL1950649 ↗
Known as Stedivaze ChEMBL registry synonym — accepted as the source's own label CHEMBL1950649 ↗
Action Activate “Adenosine A2a receptor agonist” CHEMBL1950649 ↗
Modality Small molecule — CHEMBL1950649 ↗
Route Intravenous “Apadenoson single bolus IV injection 100 or 150 ug” NCT00990327 ↗
Target ADORA2A “Adenosine A2a receptor agonist” CHEMBL1950649 ↗