drugset / Trial / NCT00990327
Study of the Safety and Efficacy of Apadenoson for Detection of Myocardial Perfusion Defects Using SPECT MPI
RandomizedCrossoverTriple-blindDiagnostic
Summary
The purpose of this study is to see whether apadenoson is as effective as adenosine when used as a pharmacological stress agent in myocardial SPECT-Imaging to detect defects in the supply of blood to the heart muscle (myocardial perfusion defects). The study will also look at whether apadenoson is better tolerated than adenosine when used in SPECT-MPI.
Timeline
- Start
- 2009-11
- Primary completion
- 2012-04
- Completion
- 2012-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Adenosine | Small molecule | 140 ug/kg | Intravenous |
| Subject | Apadenoson | Small molecule | 100 ug | Intravenous |
| Subject | Apadenoson | Small molecule | 150 ug | Intravenous |