Drugs / GILORALIMAB
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GILORALIMAB

also known as ABBV-927 · PR-1614645

Monoclonal antibody targets CD40 via activation

Developed for
head and neck cancer · malignant pancreatic neoplasm · metastatic neoplasm · non-small cell lung carcinoma · triple-negative breast carcinoma
Investigated by
AbbVie

Trials 4 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04807972 May 2021 → Mar 2024 malignant pancreatic neoplasm AbbVie Terminated No outcome recorded
Phase 1 NCT03818542 Jan → Sep 2020 head and neck cancer AbbVie Terminated No outcome recorded
Phase 1 NCT03893955 May 2019 → Mar 2026 overdue metastatic neoplasm, non-small cell lung carcinoma, triple-negative breast carcinoma AbbVie Active not recruiting No outcome recorded
Phase 1 NCT02988960 Feb 2017 → Sep 2026 expected AbbVie Active not recruiting No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as GILORALIMAB ChEMBL registry synonym — accepted as the source's own label CHEMBL4594517
Known as ABBV-927 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04807972
3

NCT03893955

NCT02988960

NCT03818542

Known as PR-1614645 ChEMBL registry synonym — accepted as the source's own label CHEMBL4594517
Action Activate “Tumor necrosis factor receptor superfamily member 5 agonist” CHEMBL4594517
Modality Monoclonal antibody CHEMBL4594517
Route Intravenous “escalating intravenous (IV) doses of ABBV-927” NCT02988960
Target CD40 “Tumor necrosis factor receptor superfamily member 5 agonist” CHEMBL4594517