drugset / Trial / NCT02988960

A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors

NCT02988960

Phase 1 Active not recruiting 163 enrolled AbbVie
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a dose-escalation study designed to evaluate the safety, pharmacokinetics, and pharmacodynamics of ABBV-927, and to determine the maximum tolerated dose (MTD) or recommended Phase 2 dose (RPTD) for ABBV-927 when administered as monotherapy or as combination therapy with ABBV-181 in participants with advanced solid tumors.

Timeline

Start
2017-02-22
Primary completion
2026-09
Completion
2026-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Budigalimab Monoclonal antibody Intravenous
Subject GILORALIMAB Monoclonal antibody Intravenous

Indications

No indication recorded.