Drugs / Linaprazan glurate
last change Dec 2025 re-read 2 minutes ago

Linaprazan glurate

Small molecule

Developed for
peptic esophagitis · esophagitis
Investigated by
Jiangsu Sinorda Biomedicine Co., Ltd · Cinclus Pharma Holding AB · Parexel

Trials 9 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT03105375 Feb → Oct 2017 Cinclus Pharma Holding AB Completed No outcome recorded
Phase 15 trials
Phase 1 NCT07308041 Nov → Dec 2025 gastroesophageal reflux disease Cinclus Pharma Holding AB Completed No outcome recorded
Phase 1 NCT07294846 Sep → Dec 2025 Jiangsu Sinorda Biomedicine Co., Ltd Completed No outcome recorded
Phase 1 NCT05469854 Jul 2022 → Nov 2026 expected gastroesophageal reflux disease Cinclus Pharma Holding AB Recruiting No outcome recorded
Phase 1 NCT07107672 Jun → Jul 2022 gastroesophageal reflux disease Jiangsu Sinorda Biomedicine Co., Ltd Completed No outcome recorded
Phase 1 NCT04293965 Oct 2018 → Sep 2019 Jiangsu Sinorda Biomedicine Co., Ltd Completed No outcome recorded
Phase 22 trials
Phase 2 NCT05055128 Aug 2021 → Sep 2022 esophagitis Cinclus Pharma Holding AB Completed No outcome recorded
Phase 2 NCT04531475 Jan → Oct 2020 peptic esophagitis Jiangsu Sinorda Biomedicine Co., Ltd Completed No outcome recorded
Phase 31 trial
Phase 3 NCT07079540 Jun 2021 → Jul 2022 peptic esophagitis Jiangsu Sinorda Biomedicine Co., Ltd Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 10 sources stand behind the page.

FieldValueCited text
Known as Linaprazan glurate Linaprazan glurate, a potassium-competitive acid blocker, is in development for the treatment of erosive oesophagitis and other acid-related diseases.” PMID 40183130 Apr 2025
3

“The participants will then continue to take linaprazan glurate (Day 2 to Day 8).” NCT07308041

NCT05469854

NCT07294846

Known as Glurate de linaprazan ChEMBL registry synonym — accepted as the source's own label CHEMBL5095187
Known as Glurato de linaprazan ChEMBL registry synonym — accepted as the source's own label CHEMBL5095187
Known as X842 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04531475
4

NCT03105375

NCT07079540

NCT07107672

NCT04293965

Modality Small molecule CHEMBL5095187
Route Oral “X842 50 mg, capsule, orally, once daily” NCT04531475