Drugs / Triclosan
Triclosan
also known as
Aquasept · CH 3565 · Cloxifenol · DNDI1246774 · Innoxa · Manusept · NSC-759151 · Skinsan · +5 more
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | COLGATE TOTAL | — | 1997-07-11 | fda.gov ↗ |
Trials 10
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 34 trials · 2 met primary · 1 missed | ||||||
| Phase 3 | NCT03081962 | Feb → Aug 2017 | — | Hospital General Universitario Elche | Unknown | No outcome recorded |
| Phase 3 | NCT03191721 | Jun 2010 → Dec 2014 | periodontitis | University of Guarulhos | Completed | Met primary |
| Phase 3 | NCT00758394 | Sep → Nov 2007 | — | Colgate Palmolive | Completed | Met primary |
| Phase 3 | NCT01072201 | Jun → Dec 2007 | mucositis | Colgate Palmolive | Completed | Missed primary |
| Phase 46 trials · 1 missed | ||||||
| Phase 4 | NCT07814898 | Feb → May 2026 | gingivitis | University of Science and Technology, Yemen | Completed | No outcome recorded |
| Phase 4 | NCT04538365 | Oct 2020 | — | Centro Ortopedico y Quirurgico del Pie | Completed | Missed primary |
| Phase 4 | NCT04256824 | Feb 2020 → Oct 2023 | — | ClinAmygate | Unknown | No outcome recorded |
| Phase 4 | NCT04255927 | Feb 2020 → Mar 2022 | — | ClinAmygate | Completed | No outcome recorded |
| Phase 4 | NCT03642353 | Jan → Dec 2016 | periodontitis, aggressive | University of Campinas, Brazil | Completed | No outcome recorded |
| Phase 4 | NCT01457859 | Oct 2011 → Oct 2013 | postoperative ventricular dysfunction | Rambam Health Care Campus | Unknown | No outcome recorded |
| Comparator or background therapy28 trials | ||||||
| Phase 2 | NCT01014143 Comparator | Aug → Sep 2007 | smooth surface dental caries | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT03700749 Comparator | Nov 2018 → Jul 2021 | — | University of Birmingham | Unknown | No outcome recorded |
| Phase 3 | NCT02193165 Comparator | Jul → Aug 2014 | gingivitis | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00763269 Comparator | Sep → Dec 2008 | dentin sensitivity | Colgate Palmolive | Completed | Missed primary |
| Phase 3 | NCT00762853 Comparator | May → Jun 2008 | smooth surface dental caries | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00762177 Comparator | May → Sep 2008 | — | Colgate Palmolive | Completed | Missed primary |
| Phase 3 | NCT00758290 Background | May → Jul 2008 | gingival disorder | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00762450 Comparator | Apr → Aug 2008 | smooth surface dental caries | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT01024738 Comparator | Mar → Apr 2008 | — | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00758563 Comparator | Mar → Apr 2008 | — | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00763048 Comparator | Mar → Apr 2008 | gingival disorder | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00761930 Comparator | Mar → Jun 2008 | gingival disorder | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00762515 Comparator | Feb → Aug 2008 | — | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00926029 Comparator | Jan → Apr 2008 | — | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00759187 Comparator | Jan → Apr 2008 | gingival disorder | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00765167 Comparator | Nov → Dec 2007 | — | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00981825 Comparator | Oct → Dec 2007 | — | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00966953 Comparator | Oct 2007 → Jan 2008 | gingival disorder | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00926328 Comparator | Jun → Dec 2007 | gingivitis | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00762619 Comparator | Apr 2007 → Aug 2008 | gingival disorder | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00763256 Comparator | May 2006 → Aug 2009 | periodontal disorder | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT00763165 Comparator | Nov 2000 → Dec 2009 | periodontal disorder | Colgate Palmolive | Unknown | No outcome recorded |
| Phase 4 | NCT05330650 Comparator | Nov 2020 → May 2021 | — | Tunis University | Completed | No outcome recorded |
| Phase 4 | NCT02670135 Comparator | Jun 2015 → Jul 2016 | periodontal disorder | Colgate Palmolive | Completed | No outcome recorded |
| Phase 4 | NCT02366689 Comparator | Jun → Dec 2014 | gingivitis | Colgate Palmolive | Completed | No outcome recorded |
| Phase 4 | NCT02360995 Comparator | Jun → Aug 2014 | gingivitis | Colgate Palmolive | Completed | No outcome recorded |
| Phase 4 | NCT00762528 Comparator | Feb 2009 → Feb 2010 | gingivitis | Colgate Palmolive | Completed | No outcome recorded |
| — | NCT03659344 Comparator | Sep 2016 → Feb 2018 | infectious disease | Shiraz University of Medical Sciences | Completed | No outcome recorded |
Evidence & citations 16 cited values
Every value below carries the sentence it was read from. 39 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Triclosan | “Comparing the incidence of SSI in cases using coated Polyglactin 910 suture with Triclosan and cases using Polyglactin 910 suture without Triclosan” NCT04256824 ↗36“OBJECTIVES: To assess the effectiveness of Triclosan coated suture in reducing surgical site infections (SSIs) rate after caesarian delivery (CD).” PMID 36520813 ↗ Dec 2022 “fascial closure with Triclosan-impregnated polyglactin suture” NCT03081962 ↗ “Using vicryl sutures which coated with triclosan (antibiotic)” NCT03659344 ↗ “2% alcoholic chlorhexidine triclosan coated suture” NCT03700749 ↗ “Coated Polyglactin 910 with Triclosan” NCT04255927 ↗ |
| Known as | Aquasept | ChEMBL registry synonym — accepted as the source's own label CHEMBL849 ↗ |
| Known as | CH 3565 | ChEMBL registry synonym — accepted as the source's own label CHEMBL849 ↗ |
| Known as | Cloxifenol | ChEMBL registry synonym — accepted as the source's own label CHEMBL849 ↗ |
| Known as | DNDI1246774 | ChEMBL registry synonym — accepted as the source's own label CHEMBL849 ↗ |
| Known as | Innoxa | ChEMBL registry synonym — accepted as the source's own label CHEMBL849 ↗ |
| Known as | Manusept | ChEMBL registry synonym — accepted as the source's own label CHEMBL849 ↗ |
| Known as | NSC-759151 | ChEMBL registry synonym — accepted as the source's own label CHEMBL849 ↗ |
| Known as | Skinsan | ChEMBL registry synonym — accepted as the source's own label CHEMBL849 ↗ |
| Known as | Stri-dex cleansing bar | ChEMBL registry synonym — accepted as the source's own label CHEMBL849 ↗ |
| Known as | Tegusept | ChEMBL registry synonym — accepted as the source's own label CHEMBL849 ↗ |
| Known as | Total toothpaste | “Brush whole mouth with Total toothpaste (triclosan/fluoride) using Total 360 toothbrush for 1 minute, 2 times/day for 6 months (study duration).” NCT02366689 ↗ |
| Known as | Triclosan component of colgate total | ChEMBL registry synonym — accepted as the source's own label CHEMBL849 ↗ |
| Known as | Triclosan/fluoride toothpaste | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02366689 ↗ |
| Modality | Small molecule | — CHEMBL849 ↗ |
| Route | Oral | “Half mouth toothbrushing twice daily for 4 days” NCT00759187 ↗ |