Drugs / LY404039
last change Jul 2020 re-read 2 minutes ago

LY404039

also known as Pomaglumetad

Small molecule targets GRM2, GRM3 via activation

Developed for
methamphetamine dependence
Investigated by
Denovo Biopharma LLC · National Institute on Drug Abuse (NIDA) · University of California, Los Angeles

Trials 2 · a red edge is where a trial was stopped

201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03106571 Aug 2017 → Jul 2020 methamphetamine dependence University of California, Los Angeles Terminated No outcome recorded
Phase 1 NCT01637142 Jul 2012 Denovo Biopharma LLC Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as LY404039 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01637142
Known as Pomaglumetad ClinicalTrials.gov intervention name — accepted as the source's own label NCT03106571
Action Activate “Metabotropic glutamate receptor 2 agonist” CHEMBL375611
1

“Metabotropic glutamate receptor 3 agonist” CHEMBL375611

Modality Small molecule CHEMBL375611
Route Intravenous “Administered IV.” NCT01637142
Target GRM2 “Metabotropic glutamate receptor 2 agonist” CHEMBL375611
Target GRM3 “Metabotropic glutamate receptor 3 agonist” CHEMBL375611