drugset / Trial / NCT03106571
Study of Pomaglumetad and Methamphetamine
Phase 1
Terminated
19 enrolled
University of California, Los Angeles
National Institute on Drug Abuse (NIDA) · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This is the first study of pomaglumetad in humans using methamphetamine. The goal of the study is to determine if pomaglumetad is safe when administered with methamphetamine. If shown to be safe with methamphetamine in the current study, a phase 2 clinical trial of pomaglumetad would be done to begin to find out if pomaglumetad is effective in treating methamphetamine use disorder.
Timeline
- Start
- 2017-08-01
- Primary completion
- 2020-07-31
- Completion
- 2020-07-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | LY404039 | Small molecule | 40 mg | Oral |
| Subject | LY404039 | Small molecule | 80 mg | Oral |
| Subject | LY404039 | Small molecule | 160 mg | Oral |
| Subject | Methamphetamine | Small molecule | 30 mg | Intravenous |